The field of psychiatry is hampered by a lack of robust, reliable and valid biomarkers that can
aid in objectively diagnosing patients and providing individualized treatment …

This review is aimed to provide a concise yet extensive survey of key short bioactive peptide
sequences for a range of applications ranging from biomaterials development to peptides …

Objective: Biomarkers are defined as anatomical, biochemical or physiological traits that are
specific to certain disorders or syndromes. The objective of this paper is to summarise the …

Decreased medial prefrontal cortex (mPFC) neuronal activity is associated with social defeat-
induced depression-and anxiety-like behaviors in mice. However, the molecular …

Cholecystokinin (CCK) has emerged as an important mammalian neuropeptide, localized in
peripheral organs and in the central nervous system. This review presents an overview of …

Many see the periaqueductal gray (PAG) as a region responsible for the downstream control
of defensive reactions. Here we provide a detailed review of anatomical and functional data …

Rehfeld, Jens F. The New Biology of Gastrointestinal Hormones. Physiol. Rev. 78: 1087–
1108, 1998.—The classic concept of gastrointestinal endocrinology is that of a few peptides …

Menstrually related symptoms and disorders are multidimensional and affect diverse
physiologic systems. Elucidation of the pathophysiologic mechanisms of these disorders …

Background Positron emission tomography (PET) allows the measurement of
benzodiazepine–γ-aminobutyric acid A (GABA A) receptor kinetics. We employed flumazenil …

The neural circuitry of fear likely underlies anxiety and fear-related disorders such as
specific and social phobia, panic disorder, and posttraumatic stress disorder. The primary …