Several developments during the past 15 years have profoundly affected our understanding
of the vomeronasal system (VNS) of vertebrates. In the mid 1990s, the vomeronasal …

In mammals, odor information detected by olfactory sensory neurons is converted to a
topographic map of activated glomeruli in the olfactory bulb. Mitral cells and tufted cells …

The mammalian central nervous system (CNS) contains a remarkable array of neural cells,
each with a complex pattern of connections that together generate perceptions and higher …

Semaphorin proteins, although initially characterized as repulsive neuronal guidance cues,
are now appreciated as major contributors to morphogenesis and homeostasis for a wide …

Gradients of axon guidance molecules have long been postulated to control the
development of the organization of neural connections into topographic maps. We review …

Neuropilins are multifunctional non–tyrosine kinase receptors that bind to class 3
semaphorins and vascular endothelial growth factor. NRP-1 and NRP-2 were first identified …

No models fully account for how odorant receptors (ORs) function in the guidance of axons
of olfactory sensory neurons (OSNs) to glomeruli in the olfactory bulb. Here, we use gene …

Hypothalamic melanocortin neurons play a pivotal role in weight regulation. Here, we
examined the contribution of Semaphorin 3 (SEMA3) signaling to the development of these …

The addition of polysialic acid to N-and/or O-linked glycans, referred to as polysialylation, is
a rare posttranslational modification that is mainly known to control the developmental …

After the successful completion of the human genome project (HGP), biological research in
the postgenome era urgently needs an efficient approach for functional analysis of genes …