It is proposed that a cognitive map encoding the relationships between entities in the world
supports flexible behavior, but the majority of the neural evidence for such a system comes …

The dentate gyrus (DG) has a key role in hippocampal memory formation. Intriguingly, DG
lesions impair many, but not all, hippocampus-dependent mnemonic functions, indicating …

The hippocampus is crucial for spatial navigation and episodic memory formation.
Hippocampal place cells exhibit spatially selective activity within an environment and have …

Hippocampal activity is critical for spatial memory. Within a fixed, familiar environment,
hippocampal codes gradually change over timescales of days to weeks—a phenomenon …

The entorhinal cortex (EC) is the brain region that often exhibits the earliest histological
alterations in Alzheimer's disease (AD), including the formation of neurofibrillary tangles and …

Since the first place cell was recorded and the cognitive-map theory was subsequently
formulated, investigation of spatial representation in the hippocampal formation has evolved …

The hippocampus plays a critical role in goal-directed navigation. Across different
environments, however, hippocampal maps are randomized, making it unclear how goal …

As animals explore an environment, the hippocampus is thought to automatically form and
maintain a place code by combining sensory and self-motion signals. Instead, we observed …

Recent studies have shown that neuronal representations gradually change over time
despite no changes in the stimulus, environment, or behavior. However, such …

The hippocampal system is critical for storage and retrieval of declarative memories,
including memories for locations and events that take place at those locations. Spatial …