Autophagy is an evolutionarily conserved, lysosome-dependent catabolic process whereby
cytoplasmic components, including damaged organelles, protein aggregates and lipid …

Diabetic cardiomyopathy is a chronic cardiovascular complication caused by diabetes that is
characterized by changes in myocardial structure and function, ultimately leading to heart …

The treatment of bone defects has plagued clinicians. Exosomes, the naturally secreted
nanovesicles by cells, exhibit great potential in bone defect regeneration to realize cell-free …

Diet-induced obesity is a major risk factor for metabolic syndrome, diabetes and
cardiovascular disease. Here, we show that a 5-d fasting-mimicking diet (FMD) …

Brown adipose tissue (BAT) activity contributes to cardiovascular health by its energy-
dissipating capacity but how BAT modulates vascular function and atherosclerosis through …

Whether bone marrow modulates systemic metabolism remains unknown. Our recent study
suggested that myeloid-derived growth factor (MYDGF) improves insulin resistance. Here …

Whether bone marrow modulates systemic metabolism remains unknown. Here, we found
that (i) myeloid cell–specific myeloid-derived growth factor (MYDGF) deficiency exacerbated …

Background: Abnormal accumulation of senescent cells in the vessel wall leads to a
compromised vascular function contributing to vascular aging. Soluble DPP4 (dipeptidyl …

BACKGROUND: Inflammation contributes to the pathogenesis of atherosclerosis. But little is
known about the potential benefits of inflammatory cells to atherosclerosis. The aim of this …

Whether bone marrow regulates bone metabolism through endocrine and paracrine
mechanism remains largely unknown. Here, we found that (i) myeloid cell‐specific myeloid …