From random to regular: Variation in the patterning of retinal mosaics
PW Keeley, SJ Eglen, BE Reese - Journal of Comparative …, 2020 - Wiley Online Library
The various types of retinal neurons are each positioned at their respective depths within the
retina where they are believed to be assembled as orderly mosaics, in which like‐type …
retina where they are believed to be assembled as orderly mosaics, in which like‐type …
Design principles and developmental mechanisms underlying retinal mosaics
BE Reese, PW Keeley - Biological Reviews, 2015 - Wiley Online Library
Most structures within the central nervous system (CNS) are composed of different types of
neuron that vary in both number and morphology, but relatively little is known about the …
neuron that vary in both number and morphology, but relatively little is known about the …
Brainwide genetic sparse cell labeling to illuminate the morphology of neurons and glia with cre-dependent MORF mice
MB Veldman, CS Park, CM Eyermann, JY Zhang… - Neuron, 2020 - cell.com
Cajal recognized that the elaborate shape of neurons is fundamental to their function in the
brain. However, there are no simple and generalizable genetic methods to study neuronal or …
brain. However, there are no simple and generalizable genetic methods to study neuronal or …
Horizontal cells, the odd ones out in the retina, give insights into development and disease
H Boije, S Shirazi Fard, PH Edqvist… - Frontiers in …, 2016 - frontiersin.org
Thorough investigation of a neuronal population can help reveal key aspects regarding the
nervous system and its development. The retinal horizontal cells have several extraordinary …
nervous system and its development. The retinal horizontal cells have several extraordinary …
ISL1 controls pancreatic alpha cell fate and beta cell maturation
R Bohuslavova, V Fabriciova, L Lebrón-Mora… - Cell & Bioscience, 2023 - Springer
Background Glucose homeostasis is dependent on functional pancreatic α and ß cells. The
mechanisms underlying the generation and maturation of these endocrine cells remain …
mechanisms underlying the generation and maturation of these endocrine cells remain …
NGL-2 regulates pathway-specific neurite growth and lamination, synapse formation, and signal transmission in the retina
F Soto, KL Watkins, RE Johnson… - Journal of …, 2013 - Soc Neuroscience
Parallel processing is an organizing principle of many neural circuits. In the retina, parallel
neuronal pathways process signals from rod and cone photoreceptors and support vision …
neuronal pathways process signals from rod and cone photoreceptors and support vision …
Retinal regeneration is facilitated by the presence of surviving neurons
T Sherpa, T Lankford, TE McGinn… - Developmental …, 2014 - Wiley Online Library
Teleost fish regenerate their retinas after damage, in contrast to mammals. In zebrafish
subjected to an extensive ouabain‐induced lesion that destroys all neurons and spares …
subjected to an extensive ouabain‐induced lesion that destroys all neurons and spares …
Sox2 regulates cholinergic amacrine cell positioning and dendritic stratification in the retina
IE Whitney, PW Keeley, AJS John… - Journal of …, 2014 - Soc Neuroscience
The retina contains two populations of cholinergic amacrine cells, one positioned in the
ganglion cell layer (GCL) and the other in the inner nuclear layer (INL), that together …
ganglion cell layer (GCL) and the other in the inner nuclear layer (INL), that together …
Independent genomic control of neuronal number across retinal cell types
PW Keeley, IE Whitney, NR Madsen, AJS John… - Developmental Cell, 2014 - cell.com
The sizes of different neuronal populations within the CNS are precisely controlled, but
whether neuronal number is coordinated between cell types is unknown. We examined the …
whether neuronal number is coordinated between cell types is unknown. We examined the …
[HTML][HTML] Distribution differences of macular cones measured by AOSLO: Variation in slope from fovea to periphery more pronounced than differences in total cones
AE Elsner, TYP Chui, L Feng, HX Song, JA Papay… - Vision research, 2017 - Elsevier
Large individual differences in cone densities occur even in healthy, young adults with low
refractive error. We investigated whether cone density follows a simple model that some …
refractive error. We investigated whether cone density follows a simple model that some …