Genome organization and genomics in Chlamydia: whole genome sequencing increases understanding of chlamydial virulence, evolution, and phylogeny

LDW Luu, V Kasimov, S Phillips, GSA Myers… - Frontiers in cellular …, 2023 - frontiersin.org
The genus Chlamydia contains important obligate intracellular bacterial pathogens to
humans and animals, including C. trachomatis and C. pneumoniae. Since 1998, when the …

Chlamydia genomics: providing novel insights into chlamydial biology

NL Bachmann, A Polkinghorne, P Timms - Trends in microbiology, 2014 - cell.com
Chlamydiaceae are obligate intracellular pathogens that have successfully evolved to
colonize a diverse range of hosts. There are currently 11 described species of Chlamydia …

Whole-genome analysis of diverse Chlamydia trachomatis strains identifies phylogenetic relationships masked by current clinical typing

SR Harris, IN Clarke, HMB Seth-Smith, AW Solomon… - Nature …, 2012 - nature.com
Chlamydia trachomatis is responsible for both trachoma and sexually transmitted infections,
causing substantial morbidity and economic cost globally. Despite this, our knowledge of its …

Genetic Variation in Chlamydia Trachomatis and Their Hosts: Impact on Disease Severity and Tissue Tropism

H Abdelsamed, J Peters, GI Byrne - Future microbiology, 2013 - Taylor & Francis
Chlamydia trachomatis infections are a global health problem. This obligate intracellular
bacterial pathogen comprises lymphogranuloma venereum (L1–L3), ocular (A–C) and …

ReporType: A Flexible Bioinformatics Tool for Targeted Loci Screening and Typing of Infectious Agents

H Cruz, M Pinheiro, V Borges - International Journal of Molecular …, 2024 - mdpi.com
In response to the pressing need for continuous monitoring of emergence and circulation of
pathogens through genomics, it is imperative to keep developing bioinformatics tools that …

Comparative Genome Analyses of Vibrio anguillarum Strains Reveal a Link with Pathogenicity Traits

D Castillo, PD Alvise, R Xu, F Zhang, M Middelboe… - Msystems, 2017 - Am Soc Microbiol
Vibrio anguillarum is a marine bacterium that can cause vibriosis in many fish and shellfish
species, leading to high mortalities and economic losses in aquaculture. Although putative …

Interplay of recombination and selection in the genomes of Chlamydia trachomatis

SJ Joseph, X Didelot, K Gandhi, D Dean, TD Read - Biology direct, 2011 - Springer
Background Chlamydia trachomatis is an obligate intracellular bacterial parasite, which
causes several severe and debilitating diseases in humans. This study uses comparative …

Chlamydia trachomatis: when the virulence-associated genome backbone imports a prevalence-associated major antigen signature

V Borges, D Cordeiro, AI Salas, Z Lodhia… - Microbial …, 2019 - microbiologyresearch.org
Chlamydia trachomatis is the most prevalent sexually transmitted bacterium worldwide and
the causative agent of trachoma. Its strains are classified according to their ompA genotypes …

Sequence variation of rare outer membrane protein β-barrel domains in clinical strains provides insights into the evolution of Treponema pallidum subsp. pallidum, the …

S Kumar, MJ Caimano, A Anand, A Dey, KL Hawley… - MBio, 2018 - Am Soc Microbiol
In recent years, considerable progress has been made in topologically and functionally
characterizing integral outer membrane proteins (OMPs) of Treponema pallidum subspecies …

Molecular characterization of atypical Chlamydia and evidence of their dissemination in different European and Asian chicken flocks by specific real‐time PCR

A Zocevic, F Vorimore, C Marhold… - Environmental …, 2012 - Wiley Online Library
Chlamydia psittaci is a zoonotic pathogen associated primarily with avian chlamydiosis.
New chlamydial agents with suspected zoonotic potential were recently detected from …