Quantitative mass spectrometry-based proteomics: an overview

S Rozanova, K Barkovits, M Nikolov, C Schmidt… - Quantitative methods in …, 2021 - Springer
In recent decades, mass spectrometry has moved more than ever before into the front line of
protein-centered research. After being established at the qualitative level, the more …

Mass spectrometry imaging: a review of emerging advancements and future insights

AR Buchberger, K DeLaney, J Johnson… - Analytical …, 2017 - pmc.ncbi.nlm.nih.gov
Mass spectrometry imaging (MSI) is a powerful tool that enables untargeted investigations
into the spatial distribution of molecular species in a variety of samples. It has the capability …

Spatial metabolomics and imaging mass spectrometry in the age of artificial intelligence

T Alexandrov - Annual review of biomedical data science, 2020 - annualreviews.org
Spatial metabolomics is an emerging field of omics research that has enabled localizing
metabolites, lipids, and drugs in tissue sections, a feat considered impossible just two …

Analysis of tissue specimens by matrix-assisted laser desorption/ionization imaging mass spectrometry in biological and clinical research

JL Norris, RM Caprioli - Chemical reviews, 2013 - ACS Publications
Human beings are adept at discerning relevant information from complex systems by
processing visual information. Similarly, as scientists labor to understand the fundamental …

Mass spectrometry imaging for plant biology: a review

BA Boughton, D Thinagaran, D Sarabia, A Bacic… - Phytochemistry …, 2016 - Springer
Mass spectrometry imaging (MSI) is a developing technique to measure the spatio-temporal
distribution of many biomolecules in tissues. Over the preceding decade, MSI has been …

MALDI imaging mass spectrometry: molecular snapshots of biochemical systems

DS Cornett, ML Reyzer, P Chaurand, RM Caprioli - Nature methods, 2007 - nature.com
Matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) is
emerging as a powerful tool for investigating the distribution of molecules within biological …

MALDI imaging mass spectrometry: spatial molecular analysis to enable a new age of discovery

MM Gessel, JL Norris, RM Caprioli - Journal of proteomics, 2014 - Elsevier
Matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI IMS)
combines the sensitivity and selectivity of mass spectrometry with spatial analysis to provide …

Ultra-high mass resolution MALDI imaging mass spectrometry of proteins and metabolites in a mouse model of glioblastoma

M Dilillo, R Ait-Belkacem, C Esteve, D Pellegrini… - Scientific reports, 2017 - nature.com
MALDI mass spectrometry imaging is able to simultaneously determine the spatial
distribution of hundreds of molecules directly from tissue sections, without labeling and …

MALDI imaging mass spectrometry: statistical data analysis and current computational challenges

T Alexandrov - BMC bioinformatics, 2012 - Springer
Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) imaging mass
spectrometry, also called MALDI-imaging, is a label-free bioanalytical technique used for …

Imaging mass spectrometry: instrumentation, applications, and combination with other visualization techniques

A Bodzon‐Kulakowska, P Suder - Mass spectrometry reviews, 2016 - Wiley Online Library
Imaging Mass Spectrometry (IMS) is strengthening its position as a valuable analytical tool. It
has unique ability to identify structures and to unravel molecular changes that occur in the …