Cardiotoxicity is a critical concern in the use of several cytotoxic drugs. Induction of
apoptosis, inflammation, and autophagy following dysregulation of the PI3K/Akt signaling …

Left ventricular (LV) mass loss is prevalent in doxorubicin (DOX)-induced cardiotoxicity and
is responsible for the progressive decline of cardiac function. Comparing to the well-studied …

Hepatotoxicity caused by chemotherapeutic drugs (eg, doxorubicin) is of critical concern in
cancer therapy. This study focused on investigating the modulatory effects of diosmin …

Backgrounds: Doxorubicin (Dox) is a classical antitumor antibiotic widely restricted for use
due to its cardiotoxicity. Daidzein (Daid) is a soy isoflavone that enhances antioxidant …

Diabetic kidney disease (DKD) is the principal cause of end-stage renal disease worldwide
and few treatments are available. Because immunomodulators are pivotal to DKD …

Doxorubicin (DOX) is a very effective broad‐spectrum anticancer drug, yet its clinical
application is badly restricted due to its serious side effects. Citronellal (CT), a specialized …

Radiation-induced enteropathy (RIE) is one of the most common and fatal complications of
abdominal radiotherapy, with no effective interventions available. Pyroptosis, a form of …

Abstract β‐LAP achone (B‐LAP) is a naphthoquinone that possesses antioxidant properties.
In the present investigation, the protective effect of B‐LAP against doxorubicin (DOX) …

Although chemotherapy drugs are extensively utilized in cancer therapy, their administration
for treatment of patients has faced problems that regardless of chemoresistance, increasing …

Abstract Context Duhuo Jisheng pill (DHJS) is a classic traditional Chinese medicine (TCM)
formula for rheumatoid arthritis (RA). The effective components and therapeutic mechanisms …