Surface-modified bacteria: synthesis, functionalization and biomedical applications

S Lin, F Wu, Y Zhang, H Chen, H Guo… - Chemical Society …, 2023 - pubs.rsc.org
The past decade has witnessed a great leap forward in bacteria-based living agents,
including imageable probes, diagnostic reagents, and therapeutics, by virtue of their unique …

Chemical technology principles for selective bioconjugation of proteins and antibodies

P Chauhan, V Ragendu, M Kumar, R Molla… - Chemical Society …, 2024 - pubs.rsc.org
Proteins are multifunctional large organic compounds that constitute an essential
component of a living system. Hence, control over their bioconjugation impacts science at …

Antibody-drug conjugates in cancer therapy: innovations, challenges, and future directions

S Kumari, S Raj, MA Babu, GK Bhatti… - Archives of Pharmacal …, 2024 - Springer
The emergence of antibody-drug conjugates (ADCs) as a potential therapeutic avenue in
cancer treatment has garnered significant attention. By combining the selective specificity of …

Recent Technological and Intellectual Property Trends in Antibody–Drug Conjugate Research

Y Choi, Y Choi, S Hong - Pharmaceutics, 2024 - mdpi.com
Antibody–drug conjugate (ADC) therapy, an advanced therapeutic technology comprising
antibodies, chemical linkers, and cytotoxic payloads, addresses the limitations of traditional …

An overview of site-specific methods for achieving antibody drug conjugates with homogenous drug to antibody ratio

DV Hingorani - Expert Opinion on Biological Therapy, 2024 - Taylor & Francis
ABSTRACT Introduction Antibody drug conjugates (ADCs) have emerged as a potent tool in
cancer treatment, where cytotoxic drugs are linked to antibodies targeting specific antigens …

[引用][C] Application of Biocatalysis for Protein Bioconjugation

TA King, LR Pérez, SL Flitsch - 2023 - Elsevier