Single-molecule experiments in biological physics: methods and applications

F Ritort - Journal of Physics: Condensed Matter, 2006 - iopscience.iop.org
I review single-molecule experiments (SMEs) in biological physics. Recent technological
developments have provided the tools to design and build scientific instruments of high …

Design and use of model membranes to study biomolecular interactions using complementary surface-sensitive techniques

LA Clifton, RA Campbell, F Sebastiani… - Advances in Colloid and …, 2020 - Elsevier
Cellular membranes are complex structures and simplified analogues in the form of model
membranes or biomembranes are used as platforms to understand fundamental properties …

[HTML][HTML] Dividing cells regulate their lipid composition and localization

GE Atilla-Gokcumen, E Muro, J Relat-Goberna… - Cell, 2014 - cell.com
Although massive membrane rearrangements occur during cell division, little is known about
specific roles that lipids might play in this process. We report that the lipidome changes with …

[图书][B] Atomic force microscopy for biologists

VJ Morris, AR Kirby, PA Gunning - 2009 - books.google.com
Atomic force microscopy (AFM) is part of a range of emerging microscopic methods for
biologists which offer the magnification range of both the light and electron microscope, but …

Influence of cholesterol on the phase transition of lipid bilayers: a temperature-controlled force spectroscopy study

L Redondo-Morata, MI Giannotti, F Sanz - Langmuir, 2012 - ACS Publications
Cholesterol (Chol) plays the essential function of regulating the physical properties of the
cell membrane by controlling the lipid organization and phase behavior and, thus, managing …

[HTML][HTML] Nanomechanics of lipid bilayers by force spectroscopy with AFM: a perspective

S Garcia-Manyes, F Sanz - Biochimica et Biophysica Acta (BBA) …, 2010 - Elsevier
Lipid bilayers determine the architecture of cell membranes and regulate a myriad of distinct
processes that are highly dependent on the lateral organization of the phospholipid …

Past, present and future of atomic force microscopy in life sciences and medicine

P Parot, YF Dufrêne, P Hinterdorfer… - Journal of Molecular …, 2007 - Wiley Online Library
To introduce this special issue of the Journal of Molecular Recognition dedicated to the
applications of atomic force microscopy (AFM) in life sciences, this paper presents a short …

[HTML][HTML] AFM for structure and dynamics of biomembranes

EI Goksu, JM Vanegas, CD Blanchette, WC Lin… - … et Biophysica Acta (BBA …, 2009 - Elsevier
We review structure and dynamic measurements of biomembranes by atomic force
microscopy (AFM). We focus mainly on studies involving supported lipid bilayers (SLBs) …

Combined AFM and two‐focus SFCS study of raft‐exhibiting model membranes

S Chiantia, J Ries, N Kahya, P Schwille - ChemPhysChem, 2006 - Wiley Online Library
Abstract Dioleoylphosphatidylcholine/sphingomyelin/cholesterol (DOPC/SM/cholesterol)
model membranes exhibit liquid–liquid phase separation and therefore provide a physical …

Mechanical properties of membranes composed of gel-phase or fluid-phase phospholipids probed on liposomes by atomic force spectroscopy

O Et-Thakafy, N Delorme, C Gaillard, C Mériadec… - Langmuir, 2017 - ACS Publications
In many liposome applications, the nanomechanical properties of the membrane envelope
are essential to ensure, eg, physical stability, protection, or penetration into tissues. Of all …