Liposomal Amphotericin B (AmBisome®): A Review of the Pharmacokinetics, Pharmacodynamics, Clinical Experience and Future Directions
Abstract Liposomal amphotericin B (AmBisome®; LAmB) is a unique lipid formulation of
amphotericin B. LAmB is a standard of care for a wide range of medically important …
amphotericin B. LAmB is a standard of care for a wide range of medically important …
Candida species: current epidemiology, pathogenicity, biofilm formation, natural antifungal products and new therapeutic options
JCO Sardi, L Scorzoni, T Bernardi… - Journal of medical …, 2013 - microbiologyresearch.org
The incidence of fungal infections has increased significantly, so contributing to morbidity
and mortality. This is caused by an increase in antimicrobial resistance and the restricted …
and mortality. This is caused by an increase in antimicrobial resistance and the restricted …
Fungal endocarditis: pathophysiology, epidemiology, clinical presentation, diagnosis, and management
GR Thompson III, JD Jenks, JW Baddley… - Clinical microbiology …, 2023 - Am Soc Microbiol
Fungal endocarditis accounts for 1% to 3% of all infective endocarditis cases, is associated
with high morbidity and mortality (> 70%), and presents numerous challenges during clinical …
with high morbidity and mortality (> 70%), and presents numerous challenges during clinical …
Understanding echinocandin resistance in the emerging pathogen Candida auris
Candida auris has simultaneously emerged on five continents as a fungal pathogen causing
nosocomial outbreaks. The challenges in the treatment of C. auris infections are the variable …
nosocomial outbreaks. The challenges in the treatment of C. auris infections are the variable …
Fungal biofilm resistance
G Ramage, R Rajendran, L Sherry… - International journal of …, 2012 - Wiley Online Library
Fungal biofilm infections have become increasingly recognised as a significant clinical
problem. One of the major reasons behind this is the impact that these have upon treatment …
problem. One of the major reasons behind this is the impact that these have upon treatment …
A simple and reproducible 96-well plate-based method for the formation of fungal biofilms and its application to antifungal susceptibility testing
The incidence of fungal infections has increased significantly over the past decades. Very
often these infections are associated with biofilm formation on implanted biomaterials and/or …
often these infections are associated with biofilm formation on implanted biomaterials and/or …
Candida biofilms and their role in infection
LJ Douglas - Trends in microbiology, 2003 - cell.com
Pathogenic fungi in the genus Candida can cause both superficial and serious systemic
disease, and are now recognized as major agents of hospital-acquired infection. Many …
disease, and are now recognized as major agents of hospital-acquired infection. Many …
Candida Infections of Medical Devices
EM Kojic, RO Darouiche - Clinical microbiology reviews, 2004 - Am Soc Microbiol
The number of indwelling medical devices is escalating, and an increasing proportion of
device-related infections are being caused by Candida spp. Candida spp. produce biofilms …
device-related infections are being caused by Candida spp. Candida spp. produce biofilms …
Pathogenesis and treatment of oral candidosis
D Williams, M Lewis - Journal of oral microbiology, 2011 - Taylor & Francis
Oral infections caused by yeast of the genus Candida and particularly Candida albicans
(oral candidoses) have been recognised throughout recorded history. However, since the …
(oral candidoses) have been recognised throughout recorded history. However, since the …
Recent insights into Candida albicans biofilm resistance mechanisms
L Mathé, P Van Dijck - Current genetics, 2013 - Springer
Like other microorganisms, free-living Candida albicans is mainly present in a three-
dimensional multicellular structure, which is called a biofilm, rather than in a planktonic form …
dimensional multicellular structure, which is called a biofilm, rather than in a planktonic form …