Abstract Liposomal amphotericin B (AmBisome®; LAmB) is a unique lipid formulation of
amphotericin B. LAmB is a standard of care for a wide range of medically important …

The incidence of fungal infections has increased significantly, so contributing to morbidity
and mortality. This is caused by an increase in antimicrobial resistance and the restricted …

Fungal endocarditis accounts for 1% to 3% of all infective endocarditis cases, is associated
with high morbidity and mortality (> 70%), and presents numerous challenges during clinical …

Candida auris has simultaneously emerged on five continents as a fungal pathogen causing
nosocomial outbreaks. The challenges in the treatment of C. auris infections are the variable …

Fungal biofilm infections have become increasingly recognised as a significant clinical
problem. One of the major reasons behind this is the impact that these have upon treatment …

The incidence of fungal infections has increased significantly over the past decades. Very
often these infections are associated with biofilm formation on implanted biomaterials and/or …

Pathogenic fungi in the genus Candida can cause both superficial and serious systemic
disease, and are now recognized as major agents of hospital-acquired infection. Many …

The number of indwelling medical devices is escalating, and an increasing proportion of
device-related infections are being caused by Candida spp. Candida spp. produce biofilms …

Oral infections caused by yeast of the genus Candida and particularly Candida albicans
(oral candidoses) have been recognised throughout recorded history. However, since the …

Like other microorganisms, free-living Candida albicans is mainly present in a three-
dimensional multicellular structure, which is called a biofilm, rather than in a planktonic form …