COVID-19 therapeutics: Challenges and directions for the future

PC Robinson, DFL Liew, HL Tanner… - Proceedings of the …, 2022 - National Acad Sciences
The emergence of SARS-CoV-2 triggering the COVID-19 pandemic ranks as arguably the
greatest medical emergency of the last century. COVID-19 has highlighted health disparities …

COVID-19 in people with rheumatic diseases: risks, outcomes, treatment considerations

R Grainger, AHJ Kim, R Conway, J Yazdany… - Nature Reviews …, 2022 - nature.com
The COVID-19 pandemic has brought challenges for people with rheumatic disease in
addition to those faced by the general population, including concerns about higher risks of …

Cellular and humoral immune responses following SARS-CoV-2 mRNA vaccination in patients with multiple sclerosis on anti-CD20 therapy

SA Apostolidis, M Kakara, MM Painter, RR Goel… - Nature medicine, 2021 - nature.com
SARS-CoV-2 messenger RNA vaccination in healthy individuals generates immune
protection against COVID-19. However, little is known about SARS-CoV-2 mRNA vaccine …

Effect of immunosuppression on the immunogenicity of mRNA vaccines to SARS-CoV-2: a prospective cohort study

P Deepak, W Kim, MA Paley, M Yang… - Annals of internal …, 2021 - acpjournals.org
Background: Patients with chronic inflammatory disease (CID) treated with
immunosuppressive medications have increased risk for severe COVID-19. Although mRNA …

American College of Rheumatology guidance for COVID‐19 vaccination in patients with rheumatic and musculoskeletal diseases: version 2

JR Curtis, SR Johnson, DD Anthony… - Arthritis & …, 2021 - Wiley Online Library
Objective To provide guidance to rheumatology providers on the use of coronavirus disease
2019 (COVID‐19) vaccines for patients with rheumatic and musculoskeletal diseases …

Immunogenicity and safety of anti-SARS-CoV-2 mRNA vaccines in patients with chronic inflammatory conditions and immunosuppressive therapy in a monocentric …

UM Geisen, DK Berner, F Tran, M Sümbül… - Annals of the …, 2021 - ard.bmj.com
Introduction In light of the SARS-CoV-2 pandemic, protecting vulnerable groups has become
a high priority. Persons at risk of severe disease, for example, those receiving …

Immunogenicity and safety of the CoronaVac inactivated vaccine in patients with autoimmune rheumatic diseases: a phase 4 trial

AC Medeiros-Ribeiro, NE Aikawa, CGS Saad… - Nature medicine, 2021 - nature.com
CoronaVac, an inactivated SARS-CoV-2 vaccine, has been approved for emergency use in
several countries. However, its immunogenicity in immunocompromised individuals has not …

Outcomes and risk factors associated with SARS-CoV-2 infection in a North American registry of patients with multiple sclerosis

A Salter, RJ Fox, SD Newsome, J Halper… - JAMA …, 2021 - jamanetwork.com
Importance Emergence of SARS-CoV-2 causing COVID-19 prompted the need to gather
information on clinical outcomes and risk factors associated with morbidity and mortality in …

[HTML][HTML] Humoral and cellular responses to mRNA vaccines against SARS-CoV-2 in patients with a history of CD20 B-cell-depleting therapy (RituxiVac): an …

MB Moor, F Suter-Riniker, MP Horn… - The Lancet …, 2021 - thelancet.com
Background B-cell-depleting therapies increase the risk of morbidity and mortality due to
COVID-19. Evidence-based SARS-CoV-2 vaccination strategies for patients on B-cell …

COVID-19 outcomes in patients with inflammatory rheumatic and musculoskeletal diseases treated with rituximab: a cohort study

J Avouac, E Drumez, E Hachulla, R Seror… - The Lancet …, 2021 - thelancet.com
Background Various observations have suggested that the course of COVID-19 might be
less favourable in patients with inflammatory rheumatic and musculoskeletal diseases …