Antimicrobial host defence peptides: functions and clinical potential
Cationic host defence peptides (CHDP), also known as antimicrobial peptides, are naturally
occurring peptides that can combat infections through their direct microbicidal properties …
occurring peptides that can combat infections through their direct microbicidal properties …
The interplay between vitamin D and viral infections
The pleiotropic role of vitamin D has been explored over the past decades and there is
compelling evidence for an epidemiological association between poor vitamin D status and …
compelling evidence for an epidemiological association between poor vitamin D status and …
Human antimicrobial peptides as therapeutics for viral infections
A Ahmed, G Siman-Tov, G Hall, N Bhalla, A Narayanan - Viruses, 2019 - mdpi.com
Successful in vivo infection following pathogen entry requires the evasion and subversion of
multiple immunological barriers. Antimicrobial peptides (AMPs) are one of the first immune …
multiple immunological barriers. Antimicrobial peptides (AMPs) are one of the first immune …
Antimicrobial mechanisms and clinical application prospects of antimicrobial peptides
X Li, S Zuo, B Wang, K Zhang, Y Wang - Molecules, 2022 - mdpi.com
Antimicrobial peptides are a type of small-molecule peptide that widely exist in nature and
are components of the innate immunity of almost all living things. They play an important role …
are components of the innate immunity of almost all living things. They play an important role …
A comprehensive summary of LL-37, the factotum human cathelicidin peptide
Cathelicidins are a group of antimicrobial peptides. Since their discovery, it has become
clear that they are an exceptional class of peptides, with some members having pleiotropic …
clear that they are an exceptional class of peptides, with some members having pleiotropic …
Immunomodulatory role of the antimicrobial LL-37 peptide in autoimmune diseases and viral infections
B Pahar, S Madonna, A Das, C Albanesi, G Girolomoni - Vaccines, 2020 - mdpi.com
Antimicrobial peptides (AMPs) are produced by neutrophils, monocytes, and macrophages,
as well as epithelial cells, and are an essential component of innate immunity system …
as well as epithelial cells, and are an essential component of innate immunity system …
Design of antimicrobial peptides: progress made with human cathelicidin LL-37
The incorporation of the innate immune system into humans is essential for survival and
health due to the rapid replication of invading microbes and the delayed action of the …
health due to the rapid replication of invading microbes and the delayed action of the …
Perspectives for clinical use of engineered human host defense antimicrobial peptides
Infectious diseases caused by bacteria, viruses or fungi are among the leading causes of
death worldwide. The emergence of drug-resistance mechanisms, especially among …
death worldwide. The emergence of drug-resistance mechanisms, especially among …
[HTML][HTML] High-quality 3D structures shine light on antibacterial, anti-biofilm and antiviral activities of human cathelicidin LL-37 and its fragments
Host defense antimicrobial peptides are key components of human innate immunity that
plays an indispensible role in human health. While there are multiple copies of cathelicidin …
plays an indispensible role in human health. While there are multiple copies of cathelicidin …
The human cathelicidin LL-37 has antiviral activity against respiratory syncytial virus
SM Currie, EG Findlay, BJ McHugh, A Mackellar… - PloS one, 2013 - journals.plos.org
Respiratory syncytial virus is a leading cause of lower respiratory tract illness among infants,
the elderly and immunocompromised individuals. Currently, there is no effective vaccine or …
the elderly and immunocompromised individuals. Currently, there is no effective vaccine or …