[HTML][HTML] Circular RNAs: Characterization, cellular roles, and applications
CX Liu, LL Chen - Cell, 2022 - cell.com
Most circular RNAs are produced from the back-splicing of exons of precursor mRNAs.
Recent technological advances have in part overcome problems with their circular …
Recent technological advances have in part overcome problems with their circular …
Coding, or non-coding, that is the question
L Poliseno, M Lanza, PP Pandolfi - Cell Research, 2024 - nature.com
The advent of high-throughput sequencing uncovered that our genome is pervasively
transcribed into RNAs that are seemingly not translated into proteins. It was also found that …
transcribed into RNAs that are seemingly not translated into proteins. It was also found that …
Circular RNA encoded MET variant promotes glioblastoma tumorigenesis
Activated by its single ligand, hepatocyte growth factor (HGF), the receptor tyrosine kinase
MET is pivotal in promoting glioblastoma (GBM) stem cell self-renewal, invasiveness and …
MET is pivotal in promoting glioblastoma (GBM) stem cell self-renewal, invasiveness and …
A novel protein encoded by exosomal CircATG4B induces oxaliplatin resistance in colorectal cancer by promoting autophagy
Z Pan, J Zheng, J Zhang, J Lin, J Lai, Z Lyu… - Advanced …, 2022 - Wiley Online Library
Oxaliplatin is commonly used in chemotherapeutic regimens for colorectal cancer (CRC)
after surgical resection. However, acquired chemoresistance seriously affects the curative …
after surgical resection. However, acquired chemoresistance seriously affects the curative …
Circular RNA translation: novel protein isoforms and clinical significance
S Wen, J Qadir, BB Yang - Trends in molecular medicine, 2022 - cell.com
In recent years, significant attention has focused on circular RNA (circRNA) translation to
determine its clinical significance. Cap-independent translation of circRNAs driven by an …
determine its clinical significance. Cap-independent translation of circRNAs driven by an …
Understanding the roles and regulation patterns of circRNA on its host gene in tumorigenesis and tumor progression
J Wei, M Li, C Xue, S Chen, L Zheng, H Deng… - Journal of Experimental …, 2023 - Springer
Circular RNAs (circRNAs) are a novel type of endogenous non-coding RNAs, which are
covalently closed loop structures formed by precursor mRNAs (pre-mRNAs) through back …
covalently closed loop structures formed by precursor mRNAs (pre-mRNAs) through back …
Circular EZH2-encoded EZH2-92aa mediates immune evasion in glioblastoma via inhibition of surface NKG2D ligands
Glioblastoma (GBM) is a highly aggressive primary brain tumour and is resistant to nearly all
available treatments, including natural killer (NK) cell immunotherapy. However, the factors …
available treatments, including natural killer (NK) cell immunotherapy. However, the factors …
Expanding uncapped translation and emerging function of circular RNA in carcinomas and noncarcinomas
Y Wang, C Wu, Y Du, Z Li, M Li, P Hou, Z Shen, S Chu… - Molecular cancer, 2022 - Springer
Circular RNAs (circRNAs) are classified as noncoding RNAs because they are devoid of a
5'end cap and a 3'end poly (A) tail necessary for cap-dependent translation. However …
5'end cap and a 3'end poly (A) tail necessary for cap-dependent translation. However …
[PDF][PDF] IL‐6–induced cGGNBP2 encodes a protein to promote cell growth and metastasis in intrahepatic cholangiocarcinoma
H Li, T Lan, H Liu, C Liu, J Dai, L Xu, Y Cai, G Hou… - …, 2022 - Wiley Online Library
Background and Aims IL‐6–induced tumor progression has been well established through
the induction of antiapoptotic and proliferative genes. However, whether other mechanisms …
the induction of antiapoptotic and proliferative genes. However, whether other mechanisms …
[HTML][HTML] CircRAPGEF5 interacts with RBFOX2 to confer ferroptosis resistance by modulating alternative splicing of TFRC in endometrial cancer
J Zhang, S Chen, S Wei, S Cheng, R Shi, R Zhao… - Redox Biology, 2022 - Elsevier
Endometrial cancer (EC) is one of the most common gynecological cancers. Ferroptosis is a
newly identified form of cell death characterized by iron-dependent lipid peroxide …
newly identified form of cell death characterized by iron-dependent lipid peroxide …