Simple Summary L-asparaginase (L-ASNase) therapy is key for achieving the very high cure
rate of pediatric acute lymphoblastic leukemia (ALL), yet its use is mostly confined to this …

Patients diagnosed with B-cell non-Hodgkin lymphoma (B-NHL), particularly if recently
treated with anti-CD20 antibodies, are at risk of severe COVID-19 disease. Because studies …

PURPOSE Asparaginase (ASNase) is an important component of acute lymphoblastic
leukemia (ALL) treatment, but is often discontinued because of toxicity. Erwinia …

The long-term outcome of acute lymphoblastic leukemia has improved dramatically due to
the development of more effective treatment strategies. L-asparaginase (ASNase) is one of …

Abstract l-Asparaginase is an antileukemic drug long approved for clinical use to treat
childhood acute lymphoblastic leukemia, the most common cancer in this population …

Asparaginase is a basic component of chemotherapy in pediatric acute lymphoblastic
leukemia (ALL) and has played a crucial role in improving the long-term survival of this …

High-dose methotrexate (HDMTX) is important for children with acute lymphoblastic
leukemia (ALL). There is no effective treatment for patients with oral mucositis, which is a …

Among various complications associated with L-asparaginase, an essential treatment
component of virtually all protocols for childhood acute lymphoblastic leukemia (ALL) …

L-asparaginase (ASNase) is a protein that is essential for the treatment of acute
lymphoblastic leukemia (ALL). The main types of ASNase that are clinically used involve …

Background l-Asparaginase is essential in the treatment of childhood acute lymphoblastic
leukemia. If immunoglobulin G anti-l-asparaginase antibodies develop, they can lead to …