Design and application of fluorescent probes to detect cellular physical microenvironments

J Ma, R Sun, K Xia, Q Xia, Y Liu, X Zhang - Chemical Reviews, 2024 - ACS Publications
The microenvironment is indispensable for functionality of various biomacromolecules,
subcellular compartments, living cells, and organisms. In particular, physical properties …

The design and bioimaging applications of NIR fluorescent organic dyes with high brightness

J Wu, Z Shi, L Zhu, J Li, X Han, M Xu… - Advanced Optical …, 2022 - Wiley Online Library
Due to the merits of decreased photon attenuation, autofluorescence, and scattering, the
near‐infrared (NIR, 700–1700 nm) region is an important window in the field of biomedicine …

Molecular rotors: fluorescent sensors for microviscosity and conformation of biomolecules

M Paez‐Perez, MK Kuimova - Angewandte Chemie, 2024 - Wiley Online Library
The viscosity and crowding of biological environment are considered vital for the correct
cellular function, and alterations in these parameters are known to underly a number of …

Real-time polymer viscosity–catalytic activity relationships on the microscale

O Eivgi, SA Blum - Journal of the American Chemical Society, 2022 - ACS Publications
Polymer growth induces physical changes to catalyst microenvironments. Here, these
physical changes are quantified in real time and are found to influence microscale chemical …

Recent progress on small molecular temperature‐sensitive fluorescent probes

Y Sun, M Fu, M Bian, Q Zhu - Biotechnology and …, 2023 - Wiley Online Library
Temperature is an important biophysical parameter that is closely related with the metabolic
activity in living cells. Therefore, the detection of intracellular temperature changes is crucial …

A supramolecular near-infrared nanophotosensitizer from host-guest complex of lactose-capped pillar [5] arene with aza-BODIPY derivative for tumor eradication

J Li, X Lv, J Li, W Jin, Z Chen, Y Wen, Z Pei… - Organic Chemistry …, 2023 - pubs.rsc.org
Aza-BODIPY is a multifunctional near-infrared fluorescent dye, and modifications around the
aza-BODIPY core can not only construct various sensors but also generate phototherapeutic …

A red-emitting thiophene-modified BODIPY probe for fluorescence lifetime-based polarity imaging of lipid droplets in living cells

R Žvirblis, K Maleckaitė… - Journal of Materials …, 2023 - pubs.rsc.org
Intracellular polarity in lipid droplets as well as other organelles may provide useful
knowledge about various processes taking place in live cells. Therefore, small fluorophores …

Highly sensitive stretchable fiber-based temperature sensor enhanced by surface-chemically modified silver nanowires

J Ban, Y Lu, J Lu, K Jia, M Luo, Y Zhou, D Wang… - Chemical Engineering …, 2024 - Elsevier
The real-time monitoring of human temperature can facilitate efficient family health
supervision, disaster diagnosis, and treatment. To meet these requirements, there is an …

Evolving a high-performance bio-imaging tool derived from a compact fluorophore as well as creating a reaction-based fluorescent probe for precise determination of …

ZY Xu, XH Wang, SL Huang, JR Chen, HQ Luo… - Chemical Engineering …, 2023 - Elsevier
Commonly, emission of red-region fluorescence is inherently in need of substantial
conjugating segments and fused rings, which inescapably burdens fluorescent molecules in …

Give or take: effects of electron-accepting/-withdrawing groups in red-fluorescent BODIPY molecular rotors

K Maleckaitė, D Narkevičius, R Žilėnaitė… - Molecules, 2021 - mdpi.com
Mapping microviscosity, temperature, and polarity in biosystems is an important capability
that can aid in disease detection. This can be achieved using fluorescent sensors based on …