The fungal cell wall is essential for growth and survival, and is a key target for antifungal
drugs and the immune system. The cell wall must be robust but flexible, protective and …

The high rates of morbidity and mortality caused by fungal infections are associated with the
current limited antifungal arsenal and the high toxicity of the compounds. Additionally …

Pathogenic fungi reside in the intestinal microbiota but rarely cause disease. Little is known
about the interactions between fungi and the immune system that promote commensalism …

Invasive fungal infections are an important infection concern for patients with underlying
immunosuppression. Antifungal therapy is a critical component of patient care, but …

The composition and organization of the cell walls from Saccharomyces cerevisiae, Candida
albicans, Aspergillus fumigatus, Schizosaccharomyces pombe, Neurospora crassa, and …

Fungal infections due to Candida and Aspergillus species cause extensive morbidity and
mortality, especially among immunosuppressed patients, and antifungal therapy is critical to …

Candida albicans is a human opportunist pathogen that can grow as yeast, pseudohyphae,
or true hyphae in vitro and in vivo, depending on environmental conditions. Reversible …

Discriminating between commensal and pathogenic states of opportunistic pathogens is
critical for host mucosal defense and homeostasis. The opportunistic human fungal …

The significant increase in the use of antifungal agents, both for the treatment of candidiasis
and invasive aspergillosis and as azole fungicides in agricultural crop protection has …

Chitin is an essential structural polysaccharide of fungal pathogens and parasites, but its
role in human immune responses remains largely unknown. It is the second most abundant …