Vaccine development against tuberculosis before and after Covid-19
SHE Kaufmann - Frontiers in Immunology, 2023 - frontiersin.org
Coronavirus disease (Covid-19) has not only shaped awareness of the impact of infectious
diseases on global health. It has also provided instructive lessons for better prevention …
diseases on global health. It has also provided instructive lessons for better prevention …
Safety, efficacy, and immunogenicity of the NVX-CoV2373 vaccine
Introduction The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in significant morbidity and …
respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in significant morbidity and …
XBB. 1.5 spike protein COVID-19 vaccine induces broadly neutralizing and cellular immune responses against EG. 5.1 and emerging XBB variants
N Patel, JF Trost, M Guebre-Xabier, H Zhou… - Scientific Reports, 2023 - nature.com
Abstract Monovalent SARS-CoV-2 Prototype (Wuhan-Hu-1) and bivalent (Prototype+ BA.
4/5) COVID-19 vaccines have demonstrated a waning of vaccine-mediated immunity …
4/5) COVID-19 vaccines have demonstrated a waning of vaccine-mediated immunity …
A comparative immunological assessment of multiple clinical-stage adjuvants for the R21 malaria vaccine in nonhuman primates
PS Arunachalam, NY Ha, SM Dennison… - Science Translational …, 2024 - science.org
Authorization of the Matrix-M (MM)–adjuvanted R21 vaccine by three countries and its
subsequent endorsement by the World Health Organization for malaria prevention in …
subsequent endorsement by the World Health Organization for malaria prevention in …
Microarray patches: scratching the surface of vaccine delivery
Introduction Microneedles are emerging as a promising technology for vaccine delivery, with
numerous advantages over traditional needle and syringe methods. Preclinical studies have …
numerous advantages over traditional needle and syringe methods. Preclinical studies have …
Rational structure-guided design of a blood stage malaria vaccine immunogen presenting a single epitope from PfRH5
There is an urgent need for improved malaria vaccine immunogens. Invasion of erythrocytes
by Plasmodium falciparum is essential for its life cycle, preceding symptoms of disease and …
by Plasmodium falciparum is essential for its life cycle, preceding symptoms of disease and …
Pivoting to protein: the immunogenicity and safety of protein-based NVX-CoV2373 as a heterologous booster for inactivated and viral vector COVID-19 vaccines
AM Marchese, R Kalkeri, M Vadivale… - Expert Review of …, 2023 - Taylor & Francis
Introduction Approximately half of the 13.4 billion COVID-19 vaccine doses administered
globally were inactivated or viral vector platforms. The harmonization and optimization of …
globally were inactivated or viral vector platforms. The harmonization and optimization of …
Unlocking saponin biosynthesis in soapwort
S Jo, A El-Demerdash, C Owen, V Srivastava… - Nature Chemical …, 2024 - nature.com
Soapwort (Saponaria officinalis) is a flowering plant from the Caryophyllaceae family with a
long history of human use as a traditional source of soap. Its detergent properties are …
long history of human use as a traditional source of soap. Its detergent properties are …
Precision adjuvants for pediatric vaccines
A Singh, C Boggiano, DE Yin, L Polakowski… - Science Translational …, 2024 - science.org
Elucidating optimal vaccine adjuvants for harnessing age-specific immune pathways to
enhance magnitude, breadth, and durability of immunogenicity remains a key gap area in …
enhance magnitude, breadth, and durability of immunogenicity remains a key gap area in …
Three immunizations with Novavax's protein vaccines increase antibody breadth and provide durable protection from SARS-CoV-2
The immune responses to Novavax's licensed NVX-CoV2373 nanoparticle Spike protein
vaccine against SARS-CoV-2 remain incompletely understood. Here, we show in rhesus …
vaccine against SARS-CoV-2 remain incompletely understood. Here, we show in rhesus …