Sixty years of amphotericin B: an overview of the main antifungal agent used to treat invasive fungal infections

FB Cavassin, JL Baú-Carneiro, RR Vilas-Boas… - Infectious Diseases and …, 2021 - Springer
Introduced in the late 1950s, polyenes represent the oldest family of antifungal drugs. The
discovery of amphotericin B and its therapeutic uses is considered one of the most important …

[PDF][PDF] Hope on the horizon: novel fungal treatments in development

AM Rauseo, A Coler-Reilly, L Larson… - Open Forum Infectious …, 2020 - academic.oup.com
The treatment of invasive fungal infections remains challenging due to limitations in currently
available antifungal therapies including toxicity, interactions, restricted routes of …

Synthesis of silver nanocomposite based on carboxymethyl cellulose: Antibacterial, antifungal and anticancer activities

SS Salem, AH Hashem, AAM Sallam, AS Doghish… - Polymers, 2022 - mdpi.com
Traditional cancer treatments include surgery, radiation, and chemotherapy. According to
medical sources, chemotherapy is still the primary method for curing or treating cancer today …

Pseudomonas indica-Mediated Silver Nanoparticles: Antifungal and Antioxidant Biogenic Tool for Suppressing Mucormycosis Fungi

SS Salem, OM Ali, AM Reyad, KA Abd-Elsalam… - Journal of Fungi, 2022 - mdpi.com
Mucormycosis is considered one of the most dangerous invasive fungal diseases. In this
study, a facile, green and eco-friendly method was used to biosynthesize silver …

Unveiling antimicrobial and insecticidal activities of biosynthesized selenium nanoparticles using prickly pear peel waste

AH Hashem, TA Selim, MH Alruhaili, S Selim… - Journal of Functional …, 2022 - mdpi.com
In the current study, prickly pear peel waste (PPPW) extract was used for the biosynthesis of
selenium nanoparticles through a green and eco-friendly method for the first time. The …

Antimicrobial and anticancer activities of biosynthesized bimetallic silver-zinc oxide nanoparticles (Ag-ZnO NPs) using pomegranate peel extract

AH Hashem, GS El-Sayyad - Biomass Conversion and Biorefinery, 2024 - Springer
In the last two decades, nanomaterials have received much attention for the treatment of
multidrug-resistant microbes that threaten human health. In the current study, the novelty …

Current antimycotics, new prospects, and future approaches to antifungal therapy

G Wall, JL Lopez-Ribot - Antibiotics, 2020 - mdpi.com
Fungal infections represent an increasing threat to a growing number of immune-and
medically compromised patients. Fungi are eukaryotic organisms and, as such, there is a …

Current insights on antifungal therapy: Novel nanotechnology approaches for drug delivery systems and new drugs from natural sources

F Sousa, D Ferreira, S Reis, P Costa - Pharmaceuticals, 2020 - mdpi.com
The high incidence of fungal infections has become a worrisome public health issue, having
been aggravated by an increase in host predisposition factors. Despite all the drugs …

Promising antimicrobial and antibiofilm activities of reduced graphene oxide-metal oxide (RGO-NiO, RGO-AgO, and RGO-ZnO) nanocomposites

S Elbasuney, GS El-Sayyad, H Tantawy, AH Hashem - RSC advances, 2021 - pubs.rsc.org
Microbial infections are considered one of the most dangerous infections in humans due to
their resistance to most antimicrobial agents. In this study, nanocomposites based on …

Antifungals discovery: an insight into new strategies to combat antifungal resistance

AM Fuentefria, B Pippi, DF Dalla Lana… - Letters in applied …, 2018 - academic.oup.com
Undeniably, new antifungal treatments are necessary against pathogenic fungi. Fungal
infections have significantly increased in recent decades, being highlighted as important …