Hypertrophic cardiomyopathy (HCM) is a prevalent and complex cardiovascular disease
where cardiac dysfunction often associates with mutations in sarcomeric genes. Various …

Introduction Among the plethora of cells under investigation to restore a functional
myocardium, mesenchymal stromal cells (MSCs) have been granted considerable interest …

Background Hypertrophic cardiomyopathy (HCM) is a prevalent and complex cardiovascular
condition. Despite being strongly associated with genetic alterations, wide variation of …

The pericardium, which surrounds the heart, provides a unique enclosed volume and a site
for the delivery of agents to the heart and coronary arteries. While strategies for targeting the …

An alginate/halloysite nanotube (HNT) nanocomposite was developed with sustained
release of bone morphogenetic proteins (BMPs) at picogram low levels. BMP‐2, 4, and 6 …

The vascularization of tissue engineered products represents a key issue in regenerative
medicine which needs to be addressed before the translation of these protocols to the …

Twenty years since their first derivation, human pluripotent stem cell-derived cardiomyocytes
(hPSC-CMs) have shown promise in disease modelling research, while their potential for …

Hypertrophic cardiomyopathy (HCM) is a prevalent and complex cardiovascular disease
characterised by multifarious hallmarks, a heterogeneous set of clinical manifestations, and …

Bone marrow transplantation is a well-established stem cell-based therapy for the
management of malignant and nonmalignant hematological disorders. In addition to the …

Hypertrophic cardiomyopathy (HCM) is a prevalent and untreatable cardiovascular disease
with a highly complex clinical and genetic causation. HCM patients bearing similar …