2H/4H-chromene (2H/4H-ch) is an important class of heterocyclic compounds with versatile
biological profiles, a simple structure, and mild adverse effects. Researchers discovered …

Introduction: Chalcones are attractive to synthetic chemists because they are easy to
prepare, have a large number of replaceable hydrogens, thereby having significant …

This review focuses on the synthesis and biological activity of flavones and their related
flavonoidic compounds, namely flavonols and aurones. Among the biological activities of …

Novel halogenated phenoxychalcones 2a–f and their corresponding N-acetylpyrazolines 3a–
f were synthesised and evaluated for their anticancer activities against breast cancer cell …

Cancer is the deadliest disease worldwide and the development of safer chemical entities to
treat cancer is one of the major challenges of medicinal chemistry. The emergence of new …

Throughout this study, we present the victorious synthesis of a novel class of 2 (1H)-
pyridone molecules, bearing a 4-hydroxyphenyl moiety through a one-pot reaction of 2 …

Abstract A pyrrolo [1, 2-a] pyrazine-based chemical territory was expanded via construction
of new chemical library with distinctive substitution patterns, which was made possible by …

Abstract Carbonic anhydrases (CA, EC 4.2. 1.1) are Zinc metalloenzymes and are present
throughout most living organisms. Among the catalytically active isoforms are the cytosolic …

A selection of new chromeno [2, 3-b] pyridines was prepared from chromenylacrylonitriles
and N-substituted piperazines, using a novel and efficient synthetic procedure. The …

The oxo-tethered-Ru (II) precatalyst promoted the one-pot C═ C/C═ O reduction of
chalcones using sodium formate as the hydrogen source in water through asymmetric …