The neural crest (NC) is a transient embryonic stem cell-like population characterized by its
multipotency and broad developmental potential. Here, we perform NC-specific …

Early development is governed by the ability of pluripotent cells to retain the full range of
developmental potential and respond accurately to developmental cues. This property is …

The chromatin remodeler CHD8 is among the most frequently mutated genes in autism
spectrum disorder (ASD). CHD8 has a dosage-sensitive role in ASD, but when and how it …

Following implantation, mouse epiblast cells transit from a naive to a primed state in which
they are competent for both somatic and primordial germ cell (PGC) specification. Using …

Background In broiler production, breast muscle weight and intramuscular fat (IMF) content
are important economic traits. Understanding the genetic mechanisms that underlie these …

Sarcopenia has garnered considerable interest in recent years as ageing-associated
diseases constitute a significant worldwide public health burden. Nutritional supplements …

Mammals in northern regions chronically suffer from low temperatures during autumn-winter
seasons. The aim of this study was to investigate the response of intestinal amino acid …

Repeat element transcription plays a vital role in early embryonic development. The
expression of repeats such as MERVL characterises mouse embryos at the 2‐cell stage and …

Neural crest‐derived stem cells (NCSCs) are tissue‐specific stem cells derived from
multipotent neural crest cells. NCSCs are present in some adult tissues such as dorsal root …

Cell-and gene-based therapies have emerged as promising strategies for treating
neurological diseases. The sources of neural stem cells are limited while the induced …