DNA damage response and repair in ovarian cancer: Potential targets for therapeutic strategies

M Mirza-Aghazadeh-Attari, C Ostadian, AA Saei… - DNA repair, 2019 - Elsevier
Ovarian cancer is among the most lethal gynecologic malignancies with a poor survival
prognosis. The current therapeutic strategies involve surgery and chemotherapy. Research …

[HTML][HTML] Experimental models for ovarian cancer research

SI Tsang, AA Hassan, SKY To, AST Wong - Experimental Cell Research, 2022 - Elsevier
Among all gynecological malignancies, ovarian cancer (OC) accounts for the highest
mortality rate due to high therapeutic resistance, prolonged latency and a lack of effective …

Human amniotic mesenchymal stem cells inhibit hepatocellular carcinoma in tumour‐bearing mice

QW Liu, JY Li, XC Zhang, Y Liu, QY Liu… - Journal of cellular …, 2020 - Wiley Online Library
Hepatocellular carcinoma (HCC) is the third leading cause of the cancer‐related death in
the world. Human amniotic mesenchymal stem cells (hAMSCs) have been characterized …

All-Trans Retinoic Acid Attenuates Transmissible Gastroenteritis Virus-Induced Apoptosis in IPEC-J2 Cells via Inhibiting ROS-Mediated P38MAPK Signaling Pathway

J Pu, D Chen, G Tian, J He, Z Huang, P Zheng, X Mao… - Antioxidants, 2022 - mdpi.com
Transmissible gastroenteritis virus (TGEV) can cause diarrhea, dehydration, and high
mortality in piglets, which is closely related to intestinal epithelial cell apoptosis caused by …

Porcine parvovirus infection activates mitochondria-mediated apoptotic signaling pathway by inducing ROS accumulation

X Zhao, H Xiang, X Bai, N Fei, Y Huang, X Song… - Virology journal, 2016 - Springer
Background Porcine parvovirus (PPV) infection primarily causes reproductive failure of
pregnant swine and results in host cell death. Boars, as an important disseminator, shed …

DKK3 promotes renal fibrosis by increasing MFF-mediated mitochondrial dysfunction in Wnt/β-catenin pathway-dependent manner

J Song, Y Chen, Y Chen, M Qiu, W Xiang, B Ke… - Renal …, 2024 - Taylor & Francis
Background Chronic kidney disease (CKD) lacks effective treatments and renal fibrosis (RF)
is one of CKD's outcomes. Dickkopf 3 (DKK3) has been identified as an agonist in CKD …

The suppressing effects of Dkk3 expression on aggressiveness and tumorigenesis of colorectal cancer

S Zhao, C Hao, E Zhao, H Jiang, H Zheng - Frontiers in Oncology, 2020 - frontiersin.org
Dkk3 has been discovered during comparison of immortalized and parental cells. Its
expression has been shown to reduce colony formation and induce apoptosis of cancer …

Wnt antagonist as therapeutic targets in ovarian cancer

NK Perumalsamy, S Warrier, LR Perumalsamy… - … International Journal of …, 2022 - Elsevier
Ovarian cancer is a fatal malignancy in women with a low survival rate that demands new
therapeutic paradigms. Cancer cells acquire various exclusive alterations to proliferate …

[HTML][HTML] Research progress of ulinastatin in the treatment of liver diseases

S Fang, P Li, C Zhu, X Han, P Bao… - International Journal of …, 2020 - ncbi.nlm.nih.gov
Ulinastatin (UTI) is a trypsin inhibitor observed in urine. UTI can treat some diseases by
inhibiting the broad-spectrum hydrolysis activity of various enzymes and other …

[HTML][HTML] The role of Dickkopf family in cancers: From Bench to Bedside

YC Shao, Y Wei, JF Liu, XY Xu - American journal of cancer …, 2017 - ncbi.nlm.nih.gov
Numerous epidemiological studies indicate that cancer will be responsible for millions of
deaths in one year. Although multiple therapeutic strategies exist, and vast research efforts …