A comprehensive report on machine learning-based early detection of alzheimer's disease using multi-modal neuroimaging data

S Sharma, PK Mandal - ACM Computing Surveys (CSUR), 2022 - dl.acm.org
Alzheimer's Disease (AD) is a devastating neurodegenerative brain disorder with no cure.
An early identification helps patients with AD sustain a normal living. We have outlined …

[HTML][HTML] Aging brain mechanics: Progress and promise of magnetic resonance elastography

LV Hiscox, H Schwarb, MDJ McGarry, CL Johnson - Neuroimage, 2021 - Elsevier
Novel neuroimaging techniques that can sensitivity characterize healthy brain aging and
detect subtle neuropathologies have enormous potential to assist in the early detection of …

Diagnosis of Alzheimer's disease using universum support vector machine based recursive feature elimination (USVM-RFE)

B Richhariya, M Tanveer, AH Rashid… - … Signal Processing and …, 2020 - Elsevier
Alzheimer's disease is one of the most common causes of death in today's world. Magnetic
resonance imaging (MRI) provides an efficient and non-invasive approach for diagnosis of …

Patient-specific models link neurotransmitter receptor mechanisms with motor and visuospatial axes of Parkinson's disease

AF Khan, Q Adewale, SJ Lin, TR Baumeister… - Nature …, 2023 - nature.com
Parkinson's disease involves multiple neurotransmitter systems beyond the classical
dopaminergic circuit, but their influence on structural and functional alterations is not well …

Insulin resistance as a link between amyloid-beta and tau pathologies in Alzheimer's disease

RJ Mullins, TC Diehl, CW Chia… - Frontiers in aging …, 2017 - frontiersin.org
Current hypotheses and theories regarding the pathogenesis of Alzheimer's disease (AD)
heavily implicate brain insulin resistance (IR) as a key factor. Despite the many well …

Cortical microstructural changes along the Alzheimer's disease continuum

V Montal, E Vilaplana, D Alcolea… - Alzheimer's & …, 2018 - Wiley Online Library
Introduction Cortical mean diffusivity (MD) and free water fraction (FW) changes are
proposed biomarkers for Alzheimer's disease (AD). Methods We included healthy control …

Dementia risk and prevention by targeting modifiable vascular risk factors

S Tariq, PA Barber - Journal of neurochemistry, 2018 - Wiley Online Library
The incidence of dementia is expected to double in the next 20 years and will contribute to
heavy social and economic burden. Dementia is caused by neuronal loss that leads to brain …

Cortical microstructural alterations in mild cognitive impairment and Alzheimer's disease dementia

NM Vogt, JF Hunt, N Adluru, DC Dean III… - Cerebral …, 2020 - academic.oup.com
In Alzheimer's disease (AD), neurodegenerative processes are ongoing for years prior to the
time that cortical atrophy can be reliably detected using conventional neuroimaging …

Cortical microstructure in young onset Alzheimer's disease using neurite orientation dispersion and density imaging

TD Parker, CF Slattery, J Zhang… - Human brain …, 2018 - Wiley Online Library
Alzheimer's disease (AD) is associated with extensive alterations in grey matter
microstructure, but our ability to quantify this in vivo is limited. Neurite orientation dispersion …

Insulin resistance in Alzheimer's disease

T Diehl, R Mullins, D Kapogiannis - Translational Research, 2017 - Elsevier
The links between systemic insulin resistance (IR), brain-specific IR, and Alzheimer's
disease (AD) have been an extremely productive area of current research. This review will …