Differential markers of bacterial and viral infections in children for point-of-care testing

YT Tsao, YH Tsai, WT Liao, CJ Shen, CF Shen… - Trends in molecular …, 2020 - cell.com
Children suffering from infectious diseases, both bacterial and viral, are often treated with
empirical antibiotics. Keeping in mind both the menace of microorganisms and antibiotic …

[HTML][HTML] Enteric fever diagnosis: current challenges and future directions

DP Neupane, HP Dulal, J Song - Pathogens, 2021 - mdpi.com
Enteric fever is a life-threatening systemic febrile disease caused by Salmonella enterica
serovars Typhi and Paratyphi (S. Typhi and S. Paratyphi). Unfortunately, the burden of the …

[HTML][HTML] Vaccine value profile for Salmonella enterica serovar Paratyphi A

LB Martin, F Khanam, F Qadri, I Khalil, MJ Sikorski… - Vaccine, 2023 - Elsevier
In Asia, there are an estimated 12 million annual cases of enteric fever, a potentially fatal
systemic bacterial infection caused by Salmonella enterica serovars Typhi (STy) and …

[HTML][HTML] Future biomarkers for infection and inflammation in febrile children

J Zandstra, I Jongerius, TW Kuijpers - Frontiers in immunology, 2021 - frontiersin.org
Febrile patients, suffering from an infection, inflammatory disease or autoimmunity may
present with similar or overlapping clinical symptoms, which makes early diagnosis difficult …

RNA2HLA: HLA-based quality control of RNA-seq datasets

I Chelysheva, AJ Pollard… - Briefings in …, 2021 - academic.oup.com
Abstract RNA-sequencing (RNA-seq) is a widely used approach for accessing the
transcriptome in biomedical research. Studies frequently include multiple samples taken …

Diagnosing malaria from some symptoms: a machine learning approach and public health implications

HI Okagbue, PE Oguntunde, ECM Obasi… - Health and …, 2021 - Springer
Malaria is a leading cause of death in Nigeria and remains a public health concern because
of the increasing resistance of the disease to antimalarial drugs. Pregnant women and …

The current status of enteric fever diagnostics and implications for disease control

S Baker, CJ Blohmke, M Maes… - Clinical Infectious …, 2020 - academic.oup.com
Enteric (typhoid) fever remains a problem in low-and middle-income countries that lack the
infrastructure to maintain sanitation and where inadequate diagnostic methods have …

Host Transcriptional Meta-signatures Reveal Diagnostic Biomarkers for Plasmodium falciparum Malaria

NI Silva, PFL Souza, BF Silva… - The Journal of …, 2024 - academic.oup.com
Background Transcriptomics has been used to evaluate immune responses during malaria
in diverse cohorts worldwide. However, the high heterogeneity of cohorts and poor …

Diagnostics for typhoid fever: current perspectives and future outlooks for product development and access

J Sapkota, T Roberts, B Basnyat, S Baker… - Open Forum …, 2023 - academic.oup.com
Typhoid is an enteric disease caused by Salmonella Typhi. Like many febrile illnesses,
typhoid presents with nonspecific symptoms. In routine healthcare settings in low-and …

The identification of enteric fever-specific antigens for population-based serosurveillance

E Mylona, L Hefele, N Tran Vu Thieu… - The Journal of …, 2024 - academic.oup.com
Background Enteric fever, caused by Salmonella enterica serovars Typhi and Paratyphi A, is
a major public health problem in low-and middle-income countries. Moderate sensitivity and …