Chemokines, small pro-inflammatory chemoattractant cytokines, that bind to specific G-
protein-coupled seven-span transmembrane receptors present on plasma membranes of …

The α‐chemokine stromal‐derived factor (SDF)‐1 and the G‐protein–coupled seven‐span
transmembrane receptor CXCR4 axis regulates the trafficking of various cell types. In this …

Monocytes recruited to tissues mediate defense against microbes or contribute to
inflammatory diseases. Regulation of the number of circulating monocytes thus has …

Chemokine stromal derived factor 1 (SDF-1) is involved in trafficking of hematopoietic stem
cells (HSCs) from the bone marrow (BM) to peripheral blood (PB) and has been found to …

In order for cancer cells to successfully colonize a metastatic site, they must detach from the
primary tumor using extracellular matrix-degrading proteases, intravasate and survive in the …

Small cell lung cancer (SCLC) is an aggressive, rapidly metastazising neoplasm with a high
propensity for marrow involvement. SCLC cells express high levels of functional CXCR4 …

Tissue repair and regeneration are thought to involve resident cell proliferation as well as
the selective recruitment of circulating stem and progenitor cell populations through complex …

Small-cell lung cancer (SCLC) is an aggressive, rapidly metastasizing neoplasm. The
chemokine stromal cell-derived factor-1 (SDF-1/CXCL12) is constitutively secreted by …

Current evidence suggests that hematopoietic stem/progenitor cell (HSPC) mobilization by
granulocyte colony-stimulating factor (G-CSF) is mediated by induction of bone marrow …

Human endoglin is an RGD-containing transmembrane glycoprotein identified in vascular
endothelial cells. Although endoglin is essential for angiogenesis and its expression is up …