The present contribution reports childhood cancer incidence and survival rates as well as
time trends and geographical variation. The report is based on the databases of population …

AIM: Since the introduction of chemotherapy, survival in localised high-grade osteosarcoma
has improved considerably. However, there is still no worldwide consensus on a standard …

Background Survival and cure rates for childhood cancers in Europe have greatly improved
over the past 40 years and are mostly good, although not in all European countries. The …

BACKGROUND: Osteosarcoma, which is the most common primary bone tumor, occurs
most frequently in adolescents, but there is a second incidence peak among individuals …

Many papers on retinoblastoma open with a statement that it is the most common primary
intraocular cancer in children and a rare disease. True enough. After reflecting a little longer …

Osteosarcoma incidence rates in the United States peak in adolescence and in the elderly.
The international patterns of osteosarcoma incidence in children have been described …

In the last half of the century, advances in the systemic therapy of cancer, including
chemotherapy, hormonal therapy, targeted therapy, and immunotherapy have been …

Primary ovarian insufficiency (POI), also known as premature ovarian failure, is a disorder of
infertility characterized by amenorrhoea, low estrogen levels and increased gonadotropin …

Bone sarcomas are a clinically and molecularly heterogeneous group of malignancies
characterized by varying degrees of mesenchymal differentiation. Despite advances in …

Osteosarcoma is a primary bone malignancy that typically occurs during adolescence but
also has a second incidence peak in the elderly. It occurs most commonly in the long bones …