Prostaglandins, particularly those of the E series, are widely regarded as
immunosuppressive products of eukaryotic cells that can downregulate many aspects of B …

The relevance of cyclooxygenases (COX)-1 and-2 and their products to inflammation,
thrombosis and gastroprotection are well known. Their importance in the immune response …

In addition to their capacity to induce pain, vasodilatation and fever, prostaglandins E (PGE)
exert anti‐inflammatory activities by inhibiting the release of pro‐inflammatory cytokines by …

Follicular dendritic cells (FDCs) are stromal cells unique to primary and secondary lymphoid
follicles. Recirculating resting B cells migrate through the FDC networks, whereas antigen …

The mechanism by which PG of the E series (PGE) promote murine B lymphocyte IgE
production was investigated. We previously reported that PGE, and other agents that …

The recent demonstration that newly recruited monocytes do not die at the site of
inflammation, but migrate to draining lymph nodes, raises the question on the mechanism …

We have studied the effects of prostaglandin E2 (PGE2) on the growth and differentiation of
human tonsillar B lymphocytes cultured in the CD40 system with or without IL-4 or IL-10 …

The E-series prostaglandins (PGEs) are complex lipid regulators of B lymphocyte function.
They inhibit the growth of certain B lymphoma lines. We report that heterogeneity with …

Replication of human immunodeficiency virus type-1 (HIV-1) is highly dependent on the
state of activation of the infected cells and is modulated by interactions between viral and …

Prostaglandins of the E series (PGE) have traditionally been considered as suppressive for
immune responses; however, recent data suggest that PGE channels the immune response …