The lifespan of patients with end-stage renal disease (ESRD) is reduced, and
cardiovascular disease (CVD) accounts for a premature death in more than 50% of patients …

Leptin is an adipocyte-derived hormone that acts as a major regulator of food intake and
energy homeostasis. It circulates both as a free and as a protein-bound entity. Leptin is …

Based on in vitro data, protein-bound uremic retention solutes have increasingly been
recognized to play a pathophysiological role in the uremic syndrome. p-Cresol, a …

Adiposity contributes to inflammation and oxidative stress in the general population, but this
association has not been examined in the chronic kidney disease (CKD) population. We …

Leptin is produced primarily by adipocytes and functions in a feedback loop regulating body
weight. Leptin deficiency results in severe obesity and a variety of endocrine abnormalities …

Aims Adipose tissue is considered as an endocrine organ that releases bioactive factors
known as adipokines which contribute to the pathogenesis of rotundity-linked metabolic and …

The association of high body mass index (BMI) with better survival in chronic kidney disease
(CKD) is considered a “risk factor paradox” or “reverse epidemiology.” Since malnutrition is a …

Objective. We sought to determine the association between plasma and SF levels of leptin
and adiponectin in patients with knee OA. Methods. Plasma and SF levels of adipokines and …

Several studies have demonstrated a strong relation between periodontal diseases and
chronic kidney disease (CKD). The main mechanisms at the base of this link are …

Although a number of pro-inflammatory [such as tumour necrosis factor (TNF)-a and
interleukin (IL)-1] and anti-inflammatory (such as IL-10) cytokines orchestrate the …