The epigenetic clock is defined by the DNA methylation (DNAm) level and has been
extensively applied to distinguish biological age from chronological age. Aging-related …

Superoxide dismutase (SOD) is a class of enzymes that restrict the biological oxidant cluster
enzyme system in the body, which can effectively respond to cellular oxidative stress, lipid …

Background People with alcohol use disorder (AUD) may be at higher risk for COVID‐19.
Angiotensin‐converting enzyme 2 (ACE2) and transmembrane serine protease 2 …

Repeated mild traumatic brain injuries (rMTBI) affect mitochondrial homeostasis in the brain.
However, mechanisms of long-lasting neurobehavioral effects of rMTBI are largely unknown …

Reward induces activity-dependant gene expression and synaptic plasticity-related
changes. Lysine-specific histone demethylase 1 (LSD1), a key enzyme driving histone …

Epidemiological studies have shown that traumatic brain injury (TBI) increases the risk for
developing neurodegenerative diseases (NDs). However, molecular mechanisms that …

Mitochondrial biogenesis in the brain is impaired in various neurological disorders including
traumatic brain injury (TBI). The long-lasting effects of TBI may be, in part, attributed to …

Spinal cord injury (SCI) is a serious central nervous system disease. Traumatic SCI often
causes persistent neurological deficits below the injury level. Epigenetic changes occur after …

Gut microbiota serves in the development and maintenance of phenotype. However, the
underlying mechanisms are still in its infancy. The current study shows epigenetic …

Traumatic brain injury (TBI) is a kind of disease with high morbidity, mortality, and disability,
and its pathogenesis is still unclear. Research shows that nucleotide-binding …