The sweetest polymer nanoparticles: opportunities ahead for glycogen in nanomedicine

QA Besford - Soft Matter, 2024 - pubs.rsc.org
Most cells take simple sugar (α-D-glucose) and assemble it into highly dense
polysaccharide nanoparticles called glycogen. This is achieved through the action of …

Tracking the Endosomal Escape of Nanoparticles in Live Cells Using a Triplex‐Forming Oligonucleotide

SK Bhangu, L Mummolo, S Fernandes… - Advanced Functional …, 2024 - Wiley Online Library
Nanoparticle‐mediated intracellular delivery of oligonucleotides is a complex phenomenon
that depends on the architecture and the intracellular trafficking of the engineered …

Antibody-Free Glycogen Nanoparticles Engage Human Immune T Cells for Intracellular Delivery of Small Drugs or mRNA

S Fernandes, M Quattrociocchi, M Cassani, G Savazzi… - ACS …, 2024 - ACS Publications
T cells play a major role in immune defense against viral infections and diseases such as
cancer. Accordingly, developing nanoparticle (NP) systems to effectively deliver therapeutics …