Fibrinogen is an abundant protein synthesized in the liver, present in human blood plasma
at concentrations ranging from 1.5-4 g/L in healthy individuals with a normal half-life of 3-5 …

Fibrinogen is a large, complex, fibrous glycoprotein with three pairs of polypeptide chains
linked together by 29 disulfide bonds. It is 45 nm in length, with globular domains at each …

Introduction The appropriate strategy for trauma-induced coagulopathy management is
under debate. We report the treatment of major trauma using mainly coagulation factor …

Hereditary fibrinogen abnormalities comprise two classes of plasma fibrinogen defects: Type
I, afibrinogenemia or hypofibrinogenemia, which has absent or low plasma fibrinogen …

Fibrinogen, a hexameric glycoprotein encoded by three genes–FGA, FGB, FGG–clustered
on chromosome 4q is involved in the final steps of coagulation as a precursor of fibrin …

We investigated the association between haplotypes of fibrinogen alpha (FGA), beta (FGB),
and gamma (FGG), total fibrinogen levels, fibrinogen γ′(γA/γ′ plus γ′/γ′) levels, and risk …

Fibrinogen contributes to thrombosis risk in different ways. Indeed, various mutations in the
fibrinogen genes predispose to thrombosis. At the same time, high levels of fibrinogen are …

Maintaining the plasma fibrinogen concentration is important to limit excessive perioperative
blood loss. This article considers the evidence for this statement, and questions the …

The method can be profitably applied to various hitherto unyielding problems such as the
control of (low-molecular-weight) heparin therapy, the detection of lupus anticoagulant, and …

Inherited disorders of fibrinogen affect either the quantity (afibrinogenemia and
hypofibrinogenemia) or the quality (dysfibrinogenemia) of the circulating fibrinogen or both …