The brain reward circuitry in mood disorders
SJ Russo, EJ Nestler - Nature reviews neuroscience, 2013 - nature.com
Mood disorders are common and debilitating conditions characterized in part by profound
deficits in reward-related behavioural domains. A recent literature has identified important …
deficits in reward-related behavioural domains. A recent literature has identified important …
Dopaminylation of histone H3 in ventral tegmental area regulates cocaine seeking
Vulnerability to relapse during periods of attempted abstinence from cocaine use is
hypothesized to result from the rewiring of brain reward circuitries, particularly ventral …
hypothesized to result from the rewiring of brain reward circuitries, particularly ventral …
Social defeat stress induces a depression-like phenotype in adolescent male c57BL/6 mice
Exposure to stress is highly correlated with the emergence of mood-related illnesses.
Because major depressive disorder often emerges in adolescence, we assessed the effects …
Because major depressive disorder often emerges in adolescence, we assessed the effects …
Vicarious social defeat stress induces depression-related outcomes in female mice
Background Stress is a prevailing risk factor for mood-related illnesses, wherein women
represent the majority of those affected by major depression. Despite the growing literature …
represent the majority of those affected by major depression. Despite the growing literature …
Neurobiological sequelae of witnessing stressful events in adult mice
BACKGROUND: It is well known that exposure to severe stress increases the risk for
developing mood disorders. However, most chronic stress models in rodents involve at least …
developing mood disorders. However, most chronic stress models in rodents involve at least …
The role of mTOR in depression and antidepressant responses
The aim of this study was to characterize the mTOR signaling cascade in depression and the
actions that antidepressant drugs have on this pathway. Herein, a literature review was …
actions that antidepressant drugs have on this pathway. Herein, a literature review was …
Repeated ketamine exposure induces an enduring resilient phenotype in adolescent and adult rats
Background Major depressive disorder afflicts up to 10% of adolescents. However, nearly
50% of those afflicted are considered nonresponsive to available treatments. Ketamine, a …
50% of those afflicted are considered nonresponsive to available treatments. Ketamine, a …
Branched-chain amino acids as new biomarkers of major depression-a novel neurobiology of mood disorder
A Baranyi, O Amouzadeh-Ghadikolai, D von Lewinski… - PloS one, 2016 - journals.plos.org
Background The proteinogenic branched-chain amino acids (BCAAs) valine, leucine and
isoleucine might play an unrecognised crucial role in the development of depression …
isoleucine might play an unrecognised crucial role in the development of depression …
Perillyl alcohol attenuates chronic restraint stress aggravated dextran sulfate sodium-induced ulcerative colitis by modulating TLR4/NF-κB and JAK2/STAT3 signaling …
Background Ulcerative colitis (UC) is the most prevalent chronic inflammatory immune
bowel disease. The modernization of lifestyle accompanied by the stress to cope with the …
bowel disease. The modernization of lifestyle accompanied by the stress to cope with the …
Effects of chronic fluoxetine treatment on anxiety-and depressive-like behaviors in adolescent rodents–systematic review and meta-analysis
J Kryst, I Majcher-Maślanka, A Chocyk - Pharmacological Reports, 2022 - Springer
Background Drugs prescribed for psychiatric disorders in adolescence should be studied
very extensively since they can affect developing and thus highly plastic brain differently …
very extensively since they can affect developing and thus highly plastic brain differently …