The intestinal barrier is critical for maintaining intestinal homeostasis, and its dysfunction is
associated with various diseases. Recent findings have revealed the multifunctional role of …

Colorectal cancer (CRC) is the third most common cancer worldwide. One of the main
causes of colorectal cancer is inflammatory bowel disease (IBD), which includes ulcerative …

Rubus chingii Hu has been used as a functional food for a long time. A novel pectin
polysaccharide named RCHP-S from R. chingii Hu was structurally identified and explored …

The tumor microenvironment (TME) is composed of a heterogenous population of cells that
exist alongside the extracellular matrix and soluble components. These components can …

Inflammatory bowel disease (IBD) encompasses a group of non-specific chronic intestinal
inflammatory conditions of unclear etiology. The current treatment and long-term …

Non-alcoholic fatty liver disease (NAFLD) is one of the leading causes of chronic liver
diseases, affecting more than one-quarter of people worldwide. Hepatic steatosis can …

Intestinal barrier dysfunction is characterized by increased intestinal permeability to lumen
endotoxin, showing remarkable predisposition to immune enteropathy, and colorectal …

Introduction Inflammatory bowel disease (IBD) is an umbrella term that includes different
chronic inflammatory diseases of the gastrointestinal tract, most commonly Crohn's disease …

Rabeprazole is a representative of proton pump inhibitors and widely used in anti‐ulcer
treatment. However, the effect of Rabeprazole on gut barrier function remains to be …

Abstract IL-22, a pleiotropic cytokine, is known to have a profound effect on the regeneration
of damaged intestinal barriers. The tissue-protective properties of IL-22 are expected to be …