The extracellular matrix (ECM) is a complex assembly of hundreds of proteins forming the
architectural scaffold of multicellular organisms. In addition to its structural role, the ECM …

Gliomas are a diverse group of primary central nervous system tumors that affect both
children and adults. Recent studies have revealed a dynamic cross talk that occurs between …

Mass spectrometry-driven glycomics and glycoproteomics, the system-wide profiling of
detached glycans and intact glycopeptides from biological samples, respectively, are …

Introduction Immune-checkpoint inhibitors (ICIs) have emerged as a core pillar of cancer
therapy as single agents or in combination regimens both in adults and children …

Glioma is a rapidly growing and aggressive primary malignant tumor of the central nervous
system that can diffusely invade the brain tissue around, and the prognosis of patients is not …

Neurological diseases affect millions of peopleochemistryorldwide and are continuously
increasing due to the globe's aging population. Such diseases affect the nervous system …

Simple Summary Glioblastoma (GBM) is a type of primary brain cancer that is extremely
aggressive and almost always fatal. To examine the response to treatment and classify GBM …

Despite diagnostic and therapeutic improvements, glioblastoma (GB) remains one of the
most threatening brain tumor in adults, underlining the urgent need of new therapeutic …

Background Despite immunotherapies having revolutionized the treatment of advanced
cutaneous melanoma, effective and durable responses were only reported in a few patients …

The brain extracellular matrix (ECM) is a highly glycosylated environment and plays
important roles in many processes including cell communication, growth factor binding, and …