A comprehensive review of signal peptides: Structure, roles, and applications
Signal peptides (SP) are short peptides located in the N-terminal of proteins, carrying
information for protein secretion. They are ubiquitous to all prokaryotes and eukaryotes. SPs …
information for protein secretion. They are ubiquitous to all prokaryotes and eukaryotes. SPs …
Signal peptides for recombinant protein secretion in bacterial expression systems
R Freudl - Microbial cell factories, 2018 - Springer
The secretion of biotechnologically or pharmaceutically relevant recombinant proteins into
the culture supernatant of a bacterial expression host greatly facilitates their downstream …
the culture supernatant of a bacterial expression host greatly facilitates their downstream …
Enhanced Extracellular Production of IsPETase in Escherichia coli via Engineering of the pelB Signal Peptide
L Shi, H Liu, S Gao, Y Weng, L Zhu - Journal of agricultural and …, 2021 - ACS Publications
Poly (ethylene terephthalate)(PET) is one of the most commonly used plastics worldwide
and its accumulation in the environment is a global problem. PETase from Ideonella …
and its accumulation in the environment is a global problem. PETase from Ideonella …
Cutinase: characteristics, preparation, and application
Abstract Cutinases (EC 3.1. 1.74) belong to the α/β-hydrolase superfamily. They were
initially discovered because they are secreted by fungi to hydrolyze the ester bonds of the …
initially discovered because they are secreted by fungi to hydrolyze the ester bonds of the …
Bacillus subtilis: from soil bacterium to super-secreting cell factory
JM van Dijl, M Hecker - Microbial cell factories, 2013 - Springer
The biotechnology industry has become a key element in modern societies. Within this
industry, the production of recombinant enzymes and biopharmaceutical proteins is of major …
industry, the production of recombinant enzymes and biopharmaceutical proteins is of major …
The “beauty in the beast”—the multiple uses of Priestia megaterium in biotechnology
Over 30 years, the Gram-positive bacterium Priestia megaterium (previously known as
Bacillus megaterium) was systematically developed for biotechnological applications …
Bacillus megaterium) was systematically developed for biotechnological applications …
Signal peptides generated by attention-based neural networks
Short (15–30 residue) chains of amino acids at the amino termini of expressed proteins
known as signal peptides (SPs) specify secretion in living cells. We trained an attention …
known as signal peptides (SPs) specify secretion in living cells. We trained an attention …
Exploitation of Bacillus subtilis as a robust workhorse for production of heterologous proteins and beyond
W Cui, L Han, F Suo, Z Liu, L Zhou, Z Zhou - World Journal of Microbiology …, 2018 - Springer
Bacillus subtilis, belonging to the type species of Bacillus, is a type of soil-derived, low% G+
C, endospore-forming Gram-positive bacterium. After the discovery of B. subtilis 168 that …
C, endospore-forming Gram-positive bacterium. After the discovery of B. subtilis 168 that …
Tat-Independent Secretion of Polyethylene Terephthalate Hydrolase PETase in Bacillus subtilis 168 Mediated by Its Native Signal Peptide
X Huang, L Cao, Z Qin, S Li, W Kong… - Journal of agricultural …, 2018 - ACS Publications
Widespread utilization of polyethylene terephthalate (PET) has caused critical
environmental pollution. The enzymatic degradation of PET is a promising solution to this …
environmental pollution. The enzymatic degradation of PET is a promising solution to this …
Optimization of Protease Secretion in Bacillus subtilis and Bacillus licheniformis by Screening of Homologous and Heterologous Signal Peptides
C Degering, T Eggert, M Puls, J Bongaerts… - Applied and …, 2010 - Am Soc Microbiol
Bacillus subtilis and Bacillus licheniformis are widely used for the large-scale industrial
production of proteins. These strains can efficiently secrete proteins into the culture medium …
production of proteins. These strains can efficiently secrete proteins into the culture medium …