Conventional and state-of-the-art detection methods of bovine spongiform encephalopathy (BSE)
M Olech - International Journal of Molecular Sciences, 2023 - mdpi.com
Bovine spongiform encephalopathy (BSE) is a fatal neurodegenerative disease that belongs
to a group of diseases known as transmissible spongiform encephalopathies (TSEs). It is …
to a group of diseases known as transmissible spongiform encephalopathies (TSEs). It is …
[HTML][HTML] Prion disease in dromedary camels, Algeria
B Babelhadj, MA Di Bari, L Pirisinu… - Emerging infectious …, 2018 - ncbi.nlm.nih.gov
Prions cause fatal and transmissible neurodegenerative diseases, including Creutzfeldt-
Jakob disease in humans, scrapie in small ruminants, and bovine spongiform …
Jakob disease in humans, scrapie in small ruminants, and bovine spongiform …
[HTML][HTML] Novel type of chronic wasting disease detected in moose (Alces alces), Norway
L Pirisinu, L Tran, B Chiappini, I Vanni… - Emerging infectious …, 2018 - ncbi.nlm.nih.gov
Chronic wasting disease (CWD) persists in cervid populations of North America and in 2016
was detected for the first time in Europe in a wild reindeer in Norway. We report the detection …
was detected for the first time in Europe in a wild reindeer in Norway. We report the detection …
Pathogenesis, detection, and control of scrapie in sheep
ED Cassmann, JJ Greenlee - American journal of veterinary …, 2020 - Am Vet Med Assoc
In sheep, scrapie is a fatal neurologic disease that is caused by a misfolded protein called a
prion (designated PrP Sc). The normal cellular prion protein (PrP C) is encoded by an …
prion (designated PrP Sc). The normal cellular prion protein (PrP C) is encoded by an …
Small ruminant nor98 prions share biochemical features with human Gerstmann-Sträussler-Scheinker disease and variably protease-sensitive prionopathy
L Pirisinu, R Nonno, E Esposito, SL Benestad… - PloS one, 2013 - journals.plos.org
Prion diseases are classically characterized by the accumulation of pathological prion
protein (PrPSc) with the protease resistant C-terminal fragment (PrPres) of 27–30 kDa …
protein (PrPSc) with the protease resistant C-terminal fragment (PrPres) of 27–30 kDa …
Characterization of goat prions demonstrates geographical variation of scrapie strains in Europe and reveals the composite nature of prion strains
Abstract Bovine Spongiform Encephalopathy (BSE) is the only animal prion which has been
recognized as a zoonotic agent so far. The identification of BSE in two goats raised the need …
recognized as a zoonotic agent so far. The identification of BSE in two goats raised the need …
Attenuated live vaccine (Bartha-K16) caused pseudorabies (Aujeszky's disease) in sheep
H Kong, K Zhang, Y Liu, Y Shang, B Wu… - Veterinary research …, 2013 - Springer
Pseudorabies (PR, Aujeszky's disease) is an acute, contagious viral disease that affects a
wide range of domestic and wild species. In the present study, an outbreak of PR in sheep …
wide range of domestic and wild species. In the present study, an outbreak of PR in sheep …
Classical BSE dismissed as the cause of CWD in Norwegian red deer despite strain similarities between both prion agents
A Marín-Moreno, SL Benestad, T Barrio, L Pirisinu… - Veterinary …, 2024 - Springer
The first case of CWD in a Norwegian red deer was detected by a routine ELISA test and
confirmed by western blotting and immunohistochemistry in the brain stem of the animal …
confirmed by western blotting and immunohistochemistry in the brain stem of the animal …
Biochemical characterization of prion strains in bank voles
L Pirisinu, S Marcon, MA Di Bari, C D'Agostino… - Pathogens, 2013 - mdpi.com
Prions exist as different strains exhibiting distinct disease phenotypes. Currently, the
identification of prion strains is still based on biological strain typing in rodents. However, it …
identification of prion strains is still based on biological strain typing in rodents. However, it …
Four types of scrapie in goats differentiated from each other and bovine spongiform encephalopathy by biochemical methods
JPM Langeveld, L Pirisinu, JG Jacobs, M Mazza… - Veterinary …, 2019 - Springer
Scrapie in goats has been known since 1942, the archetype of prion diseases in which only
prion protein (PrP) in misfolded state (PrP Sc) acts as infectious agent with fatal …
prion protein (PrP) in misfolded state (PrP Sc) acts as infectious agent with fatal …