Hidradenitis suppurativa
R Sabat, GBE Jemec, Ł Matusiak, AB Kimball… - Nature Reviews …, 2020 - nature.com
Hidradenitis suppurativa (HS; also designated as acne inversa) is a chronic inflammatory
disorder, which affects the intertriginous skin and is associated with numerous systemic …
disorder, which affects the intertriginous skin and is associated with numerous systemic …
North American clinical management guidelines for hidradenitis suppurativa: A publication from the United States and Canadian Hidradenitis Suppurativa …
Hidradenitis suppurativa is a chronic inflammatory disorder affecting hair follicles, with
profoundly negative impact on patient quality of life. Evidence informing ideal evaluation and …
profoundly negative impact on patient quality of life. Evidence informing ideal evaluation and …
IRAK4 degrader in hidradenitis suppurativa and atopic dermatitis: a phase 1 trial
L Ackerman, G Acloque, S Bacchelli, H Schwartz… - Nature Medicine, 2023 - nature.com
Toll-like receptor–driven and interleukin-1 (IL-1) receptor–driven inflammation mediated by
IL-1 receptor–associated kinase 4 (IRAK4) is involved in the pathophysiology of hidradenitis …
IL-1 receptor–associated kinase 4 (IRAK4) is involved in the pathophysiology of hidradenitis …
Hidradenitis suppurativa: advances in diagnosis and treatment
DML Saunte, GBE Jemec - Jama, 2017 - jamanetwork.com
Importance Hidradenitis suppurativa (HS) is relatively common, with the prevalence of
0.05% to 4.10%, yet many patients receive inadequate treatment. Objective To review the …
0.05% to 4.10%, yet many patients receive inadequate treatment. Objective To review the …
Two phase 3 trials of adalimumab for hidradenitis suppurativa
AB Kimball, MM Okun, DA Williams… - … England Journal of …, 2016 - Mass Medical Soc
Background Hidradenitis suppurativa is a painful, chronic inflammatory skin disease with
few options for effective treatment. In a phase 2 trial, adalimumab, an antibody against tumor …
few options for effective treatment. In a phase 2 trial, adalimumab, an antibody against tumor …
European S1 guideline for the treatment of hidradenitis suppurativa/acne inversa
CC Zouboulis, N Desai, L Emtestam… - Journal of the …, 2015 - Wiley Online Library
Hidradenitis suppurativa/acne inversa (HS) is a chronic, inflammatory, recurrent, debilitating
skin disease of the hair follicle that usually presents after puberty with painful, deep‐seated …
skin disease of the hair follicle that usually presents after puberty with painful, deep‐seated …
Development and validation of the International Hidradenitis Suppurativa Severity Score System (IHS4), a novel dynamic scoring system to assess HS severity
CC Zouboulis, T Tzellos, A Kyrgidis… - British Journal of …, 2017 - academic.oup.com
Background A validated tool for the dynamic severity assessment of hidradenitis
suppurativa/acne inversa (HS) is lacking. Objectives To develop and validate a novel …
suppurativa/acne inversa (HS) is lacking. Objectives To develop and validate a novel …
Efficacy and safety of adalimumab in conjunction with surgery in moderate to severe hidradenitis suppurativa: the SHARPS randomized clinical trial
FG Bechara, M Podda, EP Prens, B Horváth… - JAMA …, 2021 - jamanetwork.com
Importance Surgery is a mainstay in the management of hidradenitis suppurativa (HS).
Adalimumab is the first drug approved for HS. Objective To investigate the efficacy and …
Adalimumab is the first drug approved for HS. Objective To investigate the efficacy and …
Hidradenitis suppurativa/acne inversa: a practical framework for treatment optimization–systematic review and recommendations from the HS ALLIANCE working …
CC Zouboulis, FG Bechara… - Journal of the …, 2019 - Wiley Online Library
Hidradenitis suppurativa (HS)/acne inversa is a debilitating chronic disease that remains
poorly understood and difficult to manage. Clinical practice is variable, and there is a need …
poorly understood and difficult to manage. Clinical practice is variable, and there is a need …
Efficacy and safety of bimekizumab in moderate to severe hidradenitis suppurativa: a phase 2, double-blind, placebo-controlled randomized clinical trial
Importance Hidradenitis suppurativa (HS) is a chronic inflammatory disease with a high
burden for patients and limited existing therapeutic options. Objective To evaluate the …
burden for patients and limited existing therapeutic options. Objective To evaluate the …