Elongation of the poly (A) tails of specific mRNAs in the cytoplasm is a crucial regulatory step
in oogenesis and early development of many animal species. The best studied example is …

The PABP family of proteins were originally thought of as a simple shield for the mRNA poly
(A) tail. Years of research have shown that PABPs interact not only with the poly (A) tail, but …

In animal oocytes and early embryos, mRNA poly (A)-tail length strongly influences
translational efficiency (TE), but later in development this coupling between tail length and …

DAZL proteins are germ‐cell‐specific RNA‐binding proteins essential for gametogenesis.
The precise molecular role of these proteins in germ‐cell development remains enigmatic; …

Oocyte maturation arrest is one of the important causes of female infertility, but the genetic
factors remain largely unknown. PABPC1L, a predominant poly (A)‐binding protein in …

The RNA helicase p54 (DDX6, Dhh1, Me31B, Cgh-1, RCK) is a prototypic component of P-
(rocessing) bodies in cells ranging from yeast to human. Previously, we have shown that it is …

Oocyte developmental competence is the ability of the mature oocyte to be fertilized and
subsequently drive early embryo development. Developmental competence is acquired by …

PABPs [poly (A)-binding proteins] bind to the poly (A) tail of eukaryotic mRNAs and are
conserved in species ranging from yeast to human. The prototypical cytoplasmic member …

Many steps in the control of gene expression are dependent on RNA‐binding proteins, most
of which are bi‐functional, in as much as they both bind to RNA and interact with other …

mRNA polyadenylation and deadenylation are important processes that allow rapid
regulation of gene expression in response to different cellular conditions. Almost all …