Regulatory circuitry governing fungal development, drug resistance, and disease
Pathogenic fungi have become a leading cause of human mortality due to the increasing
frequency of fungal infections in immunocompromised populations and the limited …
frequency of fungal infections in immunocompromised populations and the limited …
Aspergillus fumigatus and related species
JA Sugui, KJ Kwon-Chung… - Cold Spring …, 2015 - perspectivesinmedicine.cshlp.org
The genus Aspergillus contains etiologic agents of aspergillosis. The clinical manifestations
of the disease range from allergic reaction to invasive pulmonary infection. Among the …
of the disease range from allergic reaction to invasive pulmonary infection. Among the …
What makes Aspergillus fumigatus a successful pathogen? Genes and molecules involved in invasive aspergillosis
A Abad, JV Fernández-Molina, J Bikandi… - Revista iberoamericana …, 2010 - Elsevier
Aspergillus fumigatus is an opportunistic pathogen that causes 90% of invasive aspergillosis
(IA) due to Aspergillus genus, with a 50–95% mortality rate. It has been postulated that …
(IA) due to Aspergillus genus, with a 50–95% mortality rate. It has been postulated that …
[HTML][HTML] Aspergillus Galactosaminogalactan Mediates Adherence to Host Constituents and Conceals Hyphal β-Glucan from the Immune System
FN Gravelat, A Beauvais, H Liu, MJ Lee… - PLoS …, 2013 - journals.plos.org
Aspergillus fumigatus is the most common cause of invasive mold disease in humans. The
mechanisms underlying the adherence of this mold to host cells and macromolecules have …
mechanisms underlying the adherence of this mold to host cells and macromolecules have …
[HTML][HTML] The interface between fungal biofilms and innate immunity
Fungal biofilms are communities of adherent cells surrounded by an extracellular matrix.
These biofilms are commonly found during infection caused by a variety of fungal …
These biofilms are commonly found during infection caused by a variety of fungal …
[HTML][HTML] The fungal exopolysaccharide galactosaminogalactan mediates virulence by enhancing resistance to neutrophil extracellular traps
Of the over 250 Aspergillus species, Aspergillus fumigatus accounts for up to 80% of
invasive human infections. A. fumigatus produces galactosaminogalactan (GAG), an …
invasive human infections. A. fumigatus produces galactosaminogalactan (GAG), an …
[HTML][HTML] Interactions of Aspergillus fumigatus Conidia with Airway Epithelial Cells: A Critical Review
Aspergillus fumigatus is an environmental filamentous fungus that also acts as an
opportunistic pathogen able to cause a variety of symptoms, from an allergic response to a …
opportunistic pathogen able to cause a variety of symptoms, from an allergic response to a …
[HTML][HTML] Aspergillus fumigatus biofilms: Toward understanding how growth as a multicellular network increases antifungal resistance and disease progression
KA Morelli, JD Kerkaert, RA Cramer - PLoS Pathogens, 2021 - journals.plos.org
Aspergillus fumigatus is a saprophytic, filamentous fungus found in soils and compost and
the causative agent of several pulmonary diseases in humans, birds, and other mammals. A …
the causative agent of several pulmonary diseases in humans, birds, and other mammals. A …
Pathophysiological aspects of Aspergillus colonization in disease
Aspergillus colonization of the lower respiratory airways is common in normal people, and of
little clinical significance. However, in some patients, colonization is associated with severe …
little clinical significance. However, in some patients, colonization is associated with severe …