Computer-assisted multifactorial method development for the streamlined separation and analysis of multicomponent mixtures in (Bio) pharmaceutical settings
The (bio) pharmaceutical industry is rapidly moving towards complex drug modalities that
require a commensurate level of analytical enabling technologies that can be deployed at a …
require a commensurate level of analytical enabling technologies that can be deployed at a …
Non-destructive chromatographic determination of surface area in reverse phase chromatographic columns
M Figus, YV Kazakevich - Journal of Liquid Chromatography & …, 2024 - Taylor & Francis
One of the critical but underutilized parameters that affect chromatographic separation is an
adsorbent surface area (SA). We introduce a concept of direct determination of the total …
adsorbent surface area (SA). We introduce a concept of direct determination of the total …
Basic principles for the selection of liquid chromatographic modes for specific applications
C Calderón, M Lämmerhofer - Liquid chromatography, 2023 - Elsevier
The enormous versatility of liquid chromatography (LC) arises from the numerous retention
principles that can be exploited for generating differential retention of target analytes …
principles that can be exploited for generating differential retention of target analytes …
Introducing macrocyclic glycopeptide columns as unique achiral stationary phases: Insights from hydrophobic subtraction model and in-silico modeling
Background The need for stationary phases with unique selectivity in reversed-phase liquid
chromatography has been of utmost importance to chromatographers for advancing the …
chromatography has been of utmost importance to chromatographers for advancing the …
Non-Destructive Determination of Surface Area in Reverse Phase Chromatographic Columns
M Figus - 2024 - scholarship.shu.edu
Excess adsorption isotherms of acetonitrile and methanol from water were measured on
eight commercial columns. Columns used in this study represent the latest examples in …
eight commercial columns. Columns used in this study represent the latest examples in …
Potential of Supercritical Fluid Chromatography for the Separation of Therapeutic Peptides under Consideration of Current Pharmaceutical Guidelines
JE Neumann - 2024 - refubium.fu-berlin.de
This work explores the potential of supercritical fluid chromatography for the analysis of
peptide drugs. The regulatory aspects of peptides are more complex and challenging than …
peptide drugs. The regulatory aspects of peptides are more complex and challenging than …