The ability to produce polysaccharides with diverse biological functions is widespread in
bacteria. In lactic acid bacteria (LAB), production of polysaccharides has long been …

Mycobacterium tuberculosis (Mtb) is a very successful pathogen, strictly adapted to humans
and the cause of tuberculosis. Its success is associated with its ability to inhibit host cell …

Mycobacterium tuberculosis' success as a pathogen comes from its ability to evade
degradation by macrophages. Normally macrophages clear microorganisms that activate …

Zebrafish has earned its place among animal models of tuberculosis. Its natural pathogen,
Mycobacterium marinum, shares major virulence factors with the human pathogen …

Host-derived fatty acids are an important carbon source for pathogenic mycobacteria during
infection. How mycobacterial cells regulate the catabolism of fatty acids to serve the …

Actinobacteria is a group of diverse bacteria. Most species in this class of bacteria are
filamentous aerobes found in soil, including the genus Streptomyces perhaps best known for …

The unique cell wall of mycobacteria is essential to their viability and the target of many
clinically used anti-tuberculosis drugs and inhibitors under development. Despite intensive …

The cell walls of Gram-positive bacteria contain a variety of glycopolymers (CWGPs), a
significant proportion of which are covalently linked to the peptidoglycan (PGN) scaffolding …

LC3-associated phagocytosis (LAP) is a noncanonical autophagy process reported in recent
years and is one of the effective mechanisms of host defense against bacterial infection …

In recent years, Dictyostelium discoideum has become an important model organism to
study the cell biology of professional phagocytes. This amoeba not only shares many …