[HTML][HTML] New succinimide–thiazolidinedione hybrids as multitarget antidiabetic agents: design, synthesis, bioevaluation, and molecular modelling studies

MA Huneif, MH Mahnashi, MS Jan, M Shah… - Molecules, 2023 - mdpi.com
Diabetes mellitus (DM) is a metabolic disorder majorly arising from the pathophysiology of
the pancreas manifested as a decline in the insulin production or the tissue's resistance to …

[HTML][HTML] Natural products for chronic diseases: A ray of hope

SS Hassan, MM Abdel-Daim, T Behl, S Bungau - Molecules, 2022 - mdpi.com
This Special Issue includes many high advanced quality papers that focus on natural
products with their potent pharmacological potential targeting various areas of diseases. The …

[HTML][HTML] Antidiabetic, Antihyperlipidemic, and Antioxidant Evaluation of Phytosteroids from Notholirion thomsonianum (Royle) Stapf

MA Huneif, S Fahad, A Abdulwahab, SM Alqahtani… - Plants, 2023 - mdpi.com
Diabetes mellitus (DM) is a metabolic complication and can pose a serious challenge to
human health. DM is the main cause of many life-threatening diseases. Researchers of …

Evaluation of antidiabetic potential of Fragaria × ananass Duch., Annona squamosa Linn, and Salvia hispanica L. methanolic extract–based composite and in …

S Priyanka, SKR Namasivayam, M Thenmozhi… - Biomass Conversion …, 2024 - Springer
Abstract Formulation of effective, biocompatible therapeutic agents against diabetes is an
important need in biomedicine as conventional therapy is known to cause poor efficacy and …

[HTML][HTML] Influence of organic fertilization on growth and yield of strawberry (Fragaria× ananassa) in Kabete and Mbooni areas, Kenya

SN Ombita, SM Mwendwa, SM Mureithi - Heliyon, 2024 - cell.com
Strawberries are a valuable crop in Kenya with the potential for significant economic
contributions. However, strawberry production in the country has been facing considerable …

Phytochemical profiling, in vitro antioxidants, and antidiabetic efficacy of ethyl acetate fraction of Lespedeza cuneata on streptozotocin-induced diabetic rats

AVA Mariadoss, SJ Park, K Saravanakumar… - … Science and Pollution …, 2023 - Springer
In the recent past, phytomolecules are exponentially applied in discovering the antidiabetic
drug due to less adverse effects. This work screened the active solvent fraction of …

[HTML][HTML] Exploration of succinimide derivative as a multi-target, anti-diabetic agent: in vitro and in vivo approaches

MH Mahnashi, W Alam, MA Huneif, A Abdulwahab… - Molecules, 2023 - mdpi.com
Diabetes mellitus (DM) is counted among one of the leading challenges in the recent era,
and it is a life-threatening disorder. Compound 4-hydroxy 3-methoxy phenylacetone …

[HTML][HTML] Isolation, In Vitro and In Silico Anti-Alzheimer and Anti-Inflammatory Studies on Phytosteroids from Aerial Parts of Fragaria × ananassa Duch

MH Mahnashi, OM Alshehri - Biomolecules, 2022 - mdpi.com
Based on the pharmacological importance of different species of fragaria, this research was
carried out for the isolation of bioactive compounds from Fragaria× ananassa. Using the …

[HTML][HTML] Evaluation of Habenaria aitchisonii Reichb. for antioxidant, anti-inflammatory, and antinociceptive effects with in vivo and in silico approaches

SA Asiri, M Shabnam, R Zafar, OM Alshehri… - Frontiers in …, 2024 - frontiersin.org
Habenaria aitchisonii Reichb was analyzed in this research, including its chemical
composition and its in vitro antioxidant, anti-inflammatory, acute oral toxicity, and …

[HTML][HTML] Phenolic phytochemistry, in vitro, in silico, in vivo, and mechanistic anti-inflammatory and antioxidant evaluations of Habenaria digitata

HH Almasoudi, M Saeed Jan, MH Nahari… - Frontiers in …, 2024 - frontiersin.org
Excessive and imbalance of free radicals within the body lead to inflammation. The objective
of the current research work was to explore the anti-inflammatory and antioxidant potential of …