Unraveling plant natural chemical diversity for drug discovery purposes

E Lautié, O Russo, P Ducrot, JA Boutin - Frontiers in pharmacology, 2020 - frontiersin.org
The screening and testing of extracts against a variety of pharmacological targets in order to
benefit from the immense natural chemical diversity is a concern in many laboratories …

[PDF][PDF] Galleria mellonella–intracellular bacteria pathogen infection models: the ins and outs

M Asai, Y Li, SM Newton, BD Robertson… - FEMS Microbiology …, 2023 - academic.oup.com
Galleria mellonella (greater wax moth) larvae are used widely as surrogate infectious
disease models, due to ease of use and the presence of an innate immune system …

Phytochemistry and pharmacology of natural prenylated flavonoids

HW Lv, QL Wang, M Luo, MD Zhu, HM Liang… - Archives of Pharmacal …, 2023 - Springer
Prenylated flavonoids are a special kind of flavonoid derivative possessing one or more
prenyl groups in the parent nucleus of the flavonoid. The presence of the prenyl side chain …

Isolation of naturally occurring novel isoflavonoids: An update

N Al-Maharik - Natural product reports, 2019 - pubs.rsc.org
Covering: Jan. 2012 to Dec. 2017 This review describes the 391 new isoflavonoids isolated
and identified from natural sources between January 2012 and December 2017 …

Comprehensive review on flavonoids biological activities of Erythrina plant species

NM Fahmy, E Al-Sayed, M El-Shazly… - Industrial Crops and …, 2018 - Elsevier
Erythrina species (Fabaceae) or coral trees are widely distributed in tropical and subtropical
regions worldwide. They are used in traditional medicine for the treatment of various …

The Suzuki–Miyaura Cross-Coupling–Claisen Rearrangement–Cross-Metathesis Approach to Prenylated Isoflavones

G Kwesiga, J Greese, A Kelling… - The Journal of …, 2023 - ACS Publications
Isoflavones were synthesized via Suzuki–Miyaura coupling of 3-iodochromones and para-
methoxybenzene-and para-phenolboronic acid. In our hands, conditions commonly used for …

A pharmacological overview of alpinumisoflavone, a natural prenylated isoflavonoid

SB Ateba, MA Mvondo, S Djiogue, S Zingué… - Frontiers in …, 2019 - frontiersin.org
Over the last decade, several studies demonstrated that prenylation of flavonoids enhances
various biological activities as compared to the respective nonprenylated compounds. In line …

Ameliorative effects of flavonoids and polyketides on the rotenone induced Drosophila model of Parkinson's disease

AA Siima, F Stephano, JJE Munissi, SS Nyandoro - Neurotoxicology, 2020 - Elsevier
Parkinson's disease (PD) is a movement disorder associated with the progressive loss of
dopaminergic neurons (DA). PD treatment remains unsatisfactory as the current synthetic …

Isolation and structure characterization of flavonoids

MD Awouafack, P Tane, H Morita - Flavonoids-From Biosynthesis …, 2017 - books.google.com
Flavonoids are one of the most important classes of secondary metabolites from natural
products due to their several applications in medicine, foods, diet industries, and so on …

Flavonoids and other non-alkaloidal constituents of genus Erythrina: phytochemical review

NT Son, AI Elshamy - Combinatorial Chemistry & High …, 2021 - ingentaconnect.com
Background: Genus Erythrina belongs to family Fabaceae, which is widely distributed in
tropical and subtropical areas. It has been used in both traditional herbal medicines and …