A state-of-the-science review of using mitochondrial DNA copy number as a biomarker for environmental exposure

Q Cheng, QQ Liu, CA Lu - Environmental Pollution, 2024 - Elsevier
Mitochondria are bioenergetic, biosynthetic, and signaling organelles in eukaryotes, and
contain their own genomes, mitochondrial DNA (mtDNA), to supply energy to cells by …

The impact of maternal age on gene expression during the GV to MII transition in euploid human oocytes

P Ntostis, D Iles, G Kokkali, T Vaxevanoglou… - Human …, 2022 - academic.oup.com
STUDY QUESTION Are there age-related differences in gene expression during the
germinal vesicle (GV) to metaphase II (MII) stage transition in euploid human oocytes …

The domestic pig as a model for the study of mitochondrial inheritance

D Zuidema, P Sutovsky - Cell and tissue research, 2020 - Springer
Maternal mitochondrial inheritance is a fundamental paradigm within reproductive biology,
yet the molecular mechanisms which underlie this process remain poorly understood. The …

A single nucleotide polymorphism in COQ9 affects mitochondrial and ovarian function and fertility in Holstein cows

MS Ortega, S Wohlgemuth, P Tribulo… - Biology of …, 2017 - academic.oup.com
A single missense mutation at position 159 of coenzyme Q9 (COQ9)(G→ A; rs109301586)
has been associated with genetic variation in fertility in Holstein cattle, with the A allele …

Adjusted mitochondrial DNA quantification in human embryos may not be applicable as a biomarker of implantation potential

YX Lee, CH Chen, SY Lin, YH Lin… - Journal of Assisted …, 2019 - Springer
Objective To evaluate the feasibility of adjusted mitochondrial DNA quantification in human
embryos as a biomarker for implantation potential. Design Double-blind, observational …

mtDNA diversity in human populations highlights the merit of haplotype matching in gene therapies

EC Røyrvik, JP Burgstaller… - MHR: Basic science of …, 2016 - academic.oup.com
STUDY QUESTION Does mitochondrial DNA (mtDNA) diversity in modern human
populations potentially pose a challenge, via mtDNA segregation, to mitochondrial …

Mitochondrial-nuclear crosstalk, haplotype and copy number variation distinct in muscle fiber type, mitochondrial respiratory and metabolic enzyme activities

X Liu, N Trakooljul, F Hadlich, E Murani, K Wimmers… - Scientific Reports, 2017 - nature.com
Genes expressed in mitochondria work in concert with those expressed in the nucleus to
mediate oxidative phosphorylation (OXPHOS), a process that is relevant for muscle …

The evolution of contemporary livestock species: Insights from mitochondrial genome

K Jain, M Panigrahi, SS Nayak, D Rajawat, A Sharma… - Gene, 2024 - Elsevier
The domestication of animals marks a pivotal moment in human history, profoundly
influencing our demographic and cultural progress. This process has led to significant …

Вклад гаплотипов в формирование племенных и воспроизводительных качеств животных (обзор)

АФ Яковлев - Проблемы биологии продуктивных животных, 2019 - cyberleninka.ru
В последние десятилетия наблюдаются серьёзные проблемы с репродуктивной
функцией коров. Был открыт ряд летальных гаплотипов, связанных с рецессивными …

[HTML][HTML] Estimated heat production, blood parameters and mitochondrial DNA copy number of Nellore bulls (Bos indicus) with high and low residual feed intake

WA Baldassini, JJ Ramsey, RH Branco, SFM Bonilha… - Livestock Science, 2018 - Elsevier
Our hypothesis was that heat production, blood parameters, and mitochondrial DNA
(mtDNA) copy number differed among Nellore bulls with high and low residual feed intake …