[HTML][HTML] Macrophage-targeted nanomedicine for the diagnosis and treatment of atherosclerosis

W Chen, M Schilperoort, Y Cao, J Shi, I Tabas… - Nature Reviews …, 2022 - nature.com
Nanotechnology could improve our understanding of the pathophysiology of atherosclerosis
and contribute to the development of novel diagnostic and therapeutic strategies to further …

Meta-analysis of leukocyte diversity in atherosclerotic mouse aortas

A Zernecke, H Winkels, C Cochain… - Circulation …, 2020 - Am Heart Assoc
The diverse leukocyte infiltrate in atherosclerotic mouse aortas was recently analyzed in 9
single-cell RNA sequencing and 2 mass cytometry studies. In a comprehensive meta …

Targeting the microenvironment of vulnerable atherosclerotic plaques: an emerging diagnosis and therapy strategy for atherosclerosis

S Zhang, Y Liu, Y Cao, S Zhang, J Sun… - Advanced …, 2022 - Wiley Online Library
Atherosclerosis is considered one of the primary causes of cardiovascular diseases (CVDs).
Unpredictable rupture of the vulnerable atherosclerotic plaques triggers adverse …

[HTML][HTML] Animal models of atherosclerosis

BE Veseli, P Perrotta, GRA De Meyer, L Roth… - European journal of …, 2017 - Elsevier
An ideal animal model of atherosclerosis resembles human anatomy and pathophysiology
and has the potential to be used in medical and pharmaceutical research to obtain results …

[HTML][HTML] Conjugated linoleic acid effects on cancer, obesity, and atherosclerosis: A review of pre-clinical and human trials with current perspectives

LJ den Hartigh - Nutrients, 2019 - mdpi.com
Obesity and its comorbidities, including type 2 diabetes and cardiovascular disease, are
straining our healthcare system, necessitating the development of novel strategies for weight …

[HTML][HTML] Mechanisms of action of trans fatty acids

AB Oteng, S Kersten - Advances in nutrition, 2020 - Elsevier
Human studies have established a positive association between the intake of industrial trans
fatty acids and the development of cardiovascular diseases, leading several countries to …

Foam cell formation: A new target for fighting atherosclerosis and cardiovascular disease

EM Maguire, SWA Pearce, Q Xiao - Vascular Pharmacology, 2019 - Elsevier
During atherosclerosis, the gradual accumulation of lipids into the subendothelial space of
damaged arteries results in several lipid modification processes followed by macrophage …

Systemic PFOS and PFOA exposure and disturbed lipid homeostasis in humans: what do we know and what not?

S Fragki, H Dirven, T Fletcher… - Critical reviews in …, 2021 - Taylor & Francis
Associations between per-and polyfluoroalkyl substances (PFASs) and increased blood
lipids have been repeatedly observed in humans, but a causal relation has been debated …

[HTML][HTML] Cytokines in atherosclerosis: Key players in all stages of disease and promising therapeutic targets

DP Ramji, TS Davies - Cytokine & growth factor reviews, 2015 - Elsevier
Atherosclerosis, a chronic inflammatory disorder of the arteries, is responsible for most
deaths in westernized societies with numbers increasing at a marked rate in developing …

[HTML][HTML] Pathological effects of ionizing radiation: endothelial activation and dysfunction

B Baselet, P Sonveaux, S Baatout, A Aerts - Cellular and molecular life …, 2019 - Springer
The endothelium, a tissue that forms a single layer of cells lining various organs and cavities
of the body, especially the heart and blood as well as lymphatic vessels, plays a complex …