Clinical phenotypes of adult atopic dermatitis and related therapies

C Patruno, L Potestio, M Napolitano - Current Opinion in Allergy …, 2022 - journals.lww.com
Currently, the most relevant data are those for cyclosporine, alitretinoin, and dupilumab.
Cyclosporine and dupilumab showed to be effective in the treatment of atopic dermatitis …

Dupilumab in inflammatory skin diseases: a systematic review

H Olbrich, CD Sadik, RJ Ludwig, D Thaçi, K Boch - Biomolecules, 2023 - mdpi.com
Dupilumab was first approved for the treatment of atopic dermatitis (AD) and blocks the
signaling of interleukin (IL)-4 and-13. Several other chronic skin conditions share …

Age of onset defines two distinct profiles of atopic dermatitis in adults

P Facheris, JC Da Rosa, AD Pagan, M Angelov… - Allergy, 2023 - Wiley Online Library
Background The incidence of adult‐onset atopic dermatitis (AOAD) is increasing. However,
the unique characteristics of AOAD compared to pediatric‐onset AD persisting into …

Diagnosis and management of dermatitis, including atopic, contact, and hand eczemas

CX Chan, KA Zug - Medical Clinics, 2021 - medical.theclinics.com
The term “eczema” is derived from the Greek word “ekzein” meaning “to boil over.”
Dermatitis, a synonymous term, refers to conditions with spongiotic pathology. Acute …

The neglected twin: Nummular eczema is a variant of atopic dermatitis with codominant TH2/TH17 immune response

A Böhner, M Jargosch, NS Müller… - Journal of Allergy and …, 2023 - Elsevier
Background Nummular eczema (NE) is a common chronic inflammatory skin disease
characterized by multiple, pruritic, discoid-shaped lesions. Since the underlying immune …

[PDF][PDF] Dupilumab: a review of present indications and uses out of indication

FJ Muñoz-Bellido, E Moreno… - J Investig Allergol Clin …, 2021 - researchgate.net
Recent advances in understanding T2 inflammation have broadened the diseases in which
T2 inflammation can be involved. Dupilumab is a recently developed monoclonal antibody …

Discoid (nummular) eczema in the paediatric setting–An Australian/New Zealand narrative

S McWhirter, R Foster, A Halbert… - Australasian Journal …, 2022 - Wiley Online Library
Discoid (nummular) eczema is a common and distinctive eczema variant, which has not
been studied in depth. Although the principles of management are similar to that of classic …

Effectiveness of dupilumab in pediatric patients with a nummular phenotype of atopic dermatitis

EJ Kim, M Hlobik, T Ho - Pediatric Dermatology, 2024 - Wiley Online Library
The nummular phenotype of atopic dermatitis is clinically characterized by pruritic, coin‐
shaped plaques that are frequently recalcitrant to treatment. In this study, a retrospective …

[HTML][HTML] Nummular Dermatitis

CA Robinson, LW Love, F Farci - StatPearls [Internet], 2022 - ncbi.nlm.nih.gov
Objectives: Identify potential triggers of nummular dermatitis. Summarize the distribution and
morphologic patterns of nummular dermatitis. Review potential adjunctive tests and …

[HTML][HTML] Nummular eczema

MJ Zirwas - UpToDate [Internet]. Waltham, MA: UpToDate, 2014 - medilib.ir
INTRODUCTION—Nummular eczema, also called discoid eczema or nummular dermatitis,
is a chronic, inflammatory skin disease characterized by multiple pruritic, coin-shaped …