Extracellular matrix (ECM) collectively represents a class of naturally derived proteinaceous
biomaterials purified from harvested organs and tissues with increasing scientific focus and …

Epidermal growth factor receptor (EGFR) is the first discovered member of the receptor
tyrosine kinase superfamily and plays a fundamental role during embryogenesis and in …

We tested the feasibility and safety of human-spinal-cord-derived neural stem cell (NSI-566)
transplantation for the treatment of chronic spinal cord injury (SCI). In this clinical trial, four …

Neural stem cells (NSCs) expressing GFP were embedded into fibrin matrices containing
growth factor cocktails and grafted to sites of severe spinal cord injury. Grafted cells …

The repair of spinal cord injury (SCI) highly relies on microenvironment remodeling and
facilitating the recruitment and neuronal differentiation of endogenous stem/progenitor cells …

Abstract 3D bioprinting holds great promise toward fabricating biomimetic living constructs in
a bottom-up assembly manner. To date, various emergences of living constructs have been …

Neural stem cells exist not only in the developing mammalian nervous system but also in the
adult nervous system of all mammalian organisms, including humans. Neural stem cells can …

Neural stem cells reside in the subventricular zone (SVZ) of the adult mammalian brain. This
germinal region, which continually generates new neurons destined for the olfactory bulb, is …

Oligodendrocytes, the myelin-forming cells of the central nervous system (CNS), and
astrocytes constitute macroglia. This review deals with the recent progress related to the …

The adult mammalian subventricular zone (SVZ) contains stem cells that give rise to
neurons and glia. In vivo, SVZ progeny migrate 3–8 mm to the olfactory bulb, where they …