Cellular mechanisms underlying obesity-induced arterial stiffness

AR Aroor, G Jia, JR Sowers - American Journal of …, 2018 - journals.physiology.org
Obesity is an emerging pandemic driven by consumption of a diet rich in fat and highly
refined carbohydrates (a Western diet) and a sedentary lifestyle in both children and adults …

The role of tissue renin-angiotensin-aldosterone system in the development of endothelial dysfunction and arterial stiffness

AR Aroor, VG DeMarco, G Jia, Z Sun… - Frontiers in …, 2013 - frontiersin.org
Epidemiological studies support the notion that arterial stiffness is an independent predictor
of adverse cardiovascular events contributing significantly to systolic hypertension, impaired …

Arterial stiffness and cardiovascular therapy

M Janić, M Lunder, M Šabovič - BioMed Research International, 2014 - Wiley Online Library
The world population is aging and the number of old people is continuously increasing.
Arterial structure and function change with age, progressively leading to arterial stiffening …

The role of endothelial dysfunction in aortic aneurysms

G Siasos, K Mourouzis, E Oikonomou… - Current …, 2015 - ingentaconnect.com
Abdominal aortic aneurysm is a vascular disease which, despite the fact that it shares
common risk factors with atherosclerosis, develops in parallel but as a partly independent …

Air pollution-induced vascular dysfunction: potential role of endothelin-1 (ET-1) system

J Finch, DJ Conklin - Cardiovascular toxicology, 2016 - Springer
Exposure to air pollution negatively impacts cardiovascular health. Studies show that
increased exposure to a number of airborne pollutants increases the risk for cardiovascular …

Shenfu Injection Promotes Vasodilation by Enhancing eNOS Activity Through the PI3K/Akt Signaling Pathway In Vitro

J Zhu, W Song, S Xu, Y Ma, B Wei, H Wang… - Frontiers in …, 2020 - frontiersin.org
Vasomotor dysfunction is one of the key pathological aspects of shock and heart failure (HF).
Shenfu injection (SFI) has been widely used for the treatment of shock and HF in China …

Serum mimecan is associated with arterial stiffness in hypertensive patients

X Gu, L Zhao, J Zhu, H Gu, H Li, L Wang… - Journal of the …, 2015 - Am Heart Assoc
Background Mimecan plays an important role in endothelial and vascular smooth muscle
cell integrity and may be involved the pathology of arterial stiffness. However, the role of …

Different Risk Factors Between Cerebral Infarction and Symptomatic Cerebral Vasospasm in Patients with Aneurysmal Subarachnoid Hemorrhage

I Ozono, F Ikawa, T Hidaka, S Matsuda, S Oku… - World Neurosurgery, 2023 - Elsevier
Objective Cerebral infarction due to cerebral vasospasm (IVS) after aneurysmal
subarachnoid hemorrhage is associated with poor outcomes and symptomatic cerebral …

Therapeutic modulation of aortic stiffness

AM Hussein, G Shaaya, R Arora… - American Journal of …, 2016 - journals.lww.com
Aortic stiffness (AS) is an important predictor of cardiovascular morbidity in humans. The
present review discusses the possible pathophysiological mechanisms of AS and focuses …

Increased arterial stiffness is a predictor of delayed ischaemic stroke after subarachnoid haemorrhage

M Acampa, M Bongiorno, PE Lazzerini… - Heart, Lung and …, 2021 - Elsevier
Background Subarachnoid haemorrhage (SAH) accounts for 5–10% of strokes and its
prognosis may be influenced by different complications, including delayed cerebral …