tRNA biology has come of age, revealing an unprecedented level of understanding and
many unexpected discoveries along the way. This review highlights new findings on the …

Although the nuclear pore complex (NPC) is best known for its primary function as the key
regulator of molecular traffic between the cytoplasm and the nucleus, a growing body of …

The pathway from gene activation in the nucleus to mRNA translation and decay at specific
locations in the cytoplasm is both streamlined and highly interconnected. This review …

Nuclear pore complexes (NPCs) are vital to nuclear–cytoplasmic communication in
eukaryotes. The yeast NPC‐associated TREX‐2 complex, also known as the Thp1–Sac3 …

Much of the complex process of RNP biogenesis takes place at the gene cotranscriptionally.
The target for RNA binding and processing factors is, therefore, not a solitary RNA molecule …

Messenger RNAs undergo 5'capping, splicing, 3'-end processing, and export before
translation in the cytoplasm. It has become clear that these mRNA processing events are …

The flow of genetic information in eukaryotic cells occurs through the nucleocytoplasmic
translocation of mRNAs. Knowledge of in vivo messenger RNA export kinetics remains poor …

The activator protein 1 (AP-1) transcription factor is assembled from jun-jun, jun-fos, or jun-
atf family protein homo-or heterodimers. AP-1 belongs to the class of basic leucine zipper …

The in vivo characterization of the exact copy number and the specific function of each
composite protein within the nuclear pore complex (NPC) remains both desirable and …

The nuclear export of mRNA, in which Mex67–Mtr2 mediates movement of mature
transcripts through nuclear pores, represents the culmination of the nuclear portion of the …